Protein Alignment CG14443 and pit

DIOPT Version :9

• Sequence 1: NP_572330.2
• Gene: CG14443 / 31595
• FlyBaseID: FBgn0029880
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Alignment Length: 553
• Identity: 106/553 - (19%)
• Similarity: 222/553 - (40%)
• Gaps: 143/553 - (25%)

  Fly   141 SNSGSSSDSDSTTGSSSHGSDTGERPRMRSAVFRIHETWQSPNSFKAVKTSRENKESRSRSSSLP 205
            :||.|.||.|.....:...||..|                      ..:...|:.:|.|
  Fly    91 ANSDSESDDDEQEDEADEDSDLDE----------------------VAEVDEEDVDSGS------ 127

  Fly   206 QKRFCPSKTQNDLTYGSPEPKSPSNRGRNSWRVGMRTPWKKSQSRSMSCSSIQKILVSRSFTRSR 270
                     ::|......:.:.|             .|.||:           |:|.::|..::.
  Fly   128 ---------EDDDQQEDEDEEEP-------------VPAKKT-----------KLLPNKSKAQNG 159

  Fly   271 SPHRNTLCYQDQSKNPSRPSNYNTWKQPMDEVYNNAANYRKRHNITLTSWNMRNLPEPVLSFERS 335
            .|.::                        ||.:...:        :|.:.:.|:..:...:..:.
  Fly   160 KPAKD------------------------DEPFTVES--------SLAALDYRDSDDRSFASLKG 192

  Fly   336 GFNATILQQLEDQGYDGPTPIQAQTWSIAKEGKNIVMISGKGTGKTLGYLLPGIMKMHNQRGLMQ 400
            ..:...|:.:::.|:...|.||:::.:...:|:::|..:..|:||||.:|:|.:..::..|.:.:
  Fly   193 AVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINKLRFMPR 257

  Fly   401 HKKGPIVLILVDCREAAVM---VQREVL---YYTNPLELRTHCLLGNSQWQGHAE-----CDLLV 454
            :..|  |:|:...||.::.   |.:|::   ::|..|      ::|.|..|..:|     .::||
  Fly   258 NGTG--VIIISPTRELSMQTFGVLKELMAHHHHTYGL------VMGGSNRQVESEKLGKGINILV 314

  Fly   455 ASAGRLLQMIDNKKHVVELERCTYLVLDNIDRMIDVGLEGNICRLLCRLRPHAQLIVSSTSWSSN 519
            |:.||||..:.|....: .:....|::|.:||::::|.|..:.:::..|....|.::.|.:.::.
  Fly   315 ATPGRLLDHLQNSPDFL-YKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSATQTAR 378

  Fly   520 LKRMANKFLGQYTAIRVGEINNIGVRLQNIRQRVEVVNGLSK-------VERLMKELTAIYDTSD 577
            ::.: :|...:...|.||..:|         |....|:||.:       .:||:...|.:  ..:
  Fly   379 IEAL-SKLALKSEPIYVGVHDN---------QDTATVDGLEQGYIVCPSEKRLLVLFTFL--KKN 431

  Fly   578 IPGKVVIY------VKRQKVVEELVDLIRNCVPCEGIHGGRTAQENQGIIHDFGTGAYNIIVATQ 636
            ...||:::      ||....:...:||     |...|||.:...:.......|......|::.|.
  Fly   432 RKKKVMVFFSSCMSVKYHHELFNYIDL-----PVTSIHGKQKQTKRTTTFFQFCNAESGILLCTD 491

  Fly   637 MTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRT 669
            :.:..||:|.:.:::.||.||:..:|:.|:.||
  Fly   492 VAARGLDIPQVDWIVQYDPPDDPREYIHRVGRT 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14443	NP_572330.2	P-loop_NTPase	332..535	CDD:304359	46/213 (22%)
		DEXDc	345..544	CDD:214692	49/209 (23%)
		Helicase_C	560..670	CDD:278689	27/123 (22%)
pit	NP_001287459.1	SrmB	186..677	CDD:223587	81/365 (22%)
		DEADc	187..394	CDD:238167	47/216 (22%)
		HELICc	408..537	CDD:238034	28/124 (23%)
		DUF4217	569..627	CDD:290667

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451766
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930