Protein Alignment CG14443 and eIF4A

DIOPT Version :9

• Sequence 1: NP_572330.2
• Gene: CG14443 / 31595
• FlyBaseID: FBgn0029880
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Alignment Length: 426
• Identity: 94/426 - (22%)
• Similarity: 185/426 - (43%)
• Gaps: 51/426 - (11%)

  Fly   293 NTWKQPMDEVYNNAANYRKRHNITLTSWNMRNLPEPVLSFERSGFNATILQQLEDQGYDGPTPIQ 357
            :||    .|||:|                          |:.......:|:.:...|::.|:.||
  Fly    23 STW----HEVYDN--------------------------FDDMNLREELLRGIYGYGFEKPSAIQ 57

  Fly   358 AQTWSIAKEGKNIVMISGKGTGKTLGYLLPGIMKMHNQRGLMQHKKGPIVLILVDCREAAVMVQR 422
            .:.......|::::..:..|||||..:.:..:.::.......|      .|||...||.|..:||
  Fly    58 QRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSIRECQ------ALILAPTRELATQIQR 116

  Fly   423 EVLYYTNPLELRTHCLLGNSQWQGHAE-----CDLLVASAGRLLQMIDNKKHVVELERCTYLVLD 482
            .|:.....:::.:|..:|.:..:..|.     |.::|.:.||:..||:.|  |:..:.....|||
  Fly   117 VVMALGEYMKVHSHACIGGTNVREDARILESGCHVVVGTPGRVYDMINRK--VLRTQYIKLFVLD 179

  Fly   483 NIDRMIDVGLEGNICRLLCRLRPHAQLIVSSTSWSSNLKRMANKFLGQYTAIRVGEINNIGVRLQ 547
            ..|.|:..|.:..|..:...|.|..|:|:.|.:...::..::..|:....:|.|.:..   :.|:
  Fly   180 EADEMLSRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEE---LTLE 241

  Fly   548 NIRQRVEVVNGLSKVERLMKELTAIYDTSDIPGKVVIYVKRQKVVEELVDLIRNCVPCEGIHGGR 612
            .|:|  ..|| :.:....:..|..:|||..|...|:....|:||.:...::..:......:||..
  Fly   242 GIKQ--FYVN-VKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDM 303

  Fly   613 TAQENQGIIHDFGTGAYNIIVATQMTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRTGCLSYNRN 677
            ..::.:.|:..|.:|:..:::.|.:.:..:||..:..|||||.|.|.:.|:.|:.|.|  .:.|.
  Fly   304 EQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGG--RFGRK 366

  Fly   678 CEVISFFTMANYKLVTEVVDFLKICKQEIGPHLLQL 713
            ...|:|.|..:.:::.::..|.....:|:..::..|
  Fly   367 GVAINFITDDDRRILKDIEQFYHTTIEEMPANIADL 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14443	NP_572330.2	P-loop_NTPase	332..535	CDD:304359	46/207 (22%)
		DEXDc	345..544	CDD:214692	46/203 (23%)
		Helicase_C	560..670	CDD:278689	27/109 (25%)
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	94/426 (22%)
		DEADc	32..232	CDD:238167	46/207 (22%)
		Helicase_C	254..358	CDD:278689	26/103 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930