DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14443 and CG5800

DIOPT Version :9

Sequence 1:	NP_572330.2	Gene:	CG14443 / 31595	FlyBaseID:	FBgn0029880	Length:	736	Species:	Drosophila melanogaster
Sequence 2:	NP_573230.1	Gene:	CG5800 / 32742	FlyBaseID:	FBgn0030855	Length:	826	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	90/468 - (19%)
Similarity:	194/468 - (41%)	Gaps:	58/468 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 RPSNYNTWKQPMDEVYNNAANYRKRHNITLTSWNMRNL--------PEPVLSFERSGFNATILQQ 344
            |.|..|:.|:|..|:        .:..:..|...:::|        ...:..|.:...:....:.
  Fly    30 RKSGDNSQKRPRQEI--------NKSRLAATEAEIQDLKTKYAEIDATAIKKFAQFPLSKKTQKA 86

  Fly   345 LEDQGYDGPTPIQAQTWSIAKEGKNIVMISGKGTGKTLGYLLPGIMKMHNQRGLMQHKKGPIVLI 409
            |.:..:..||.:|..:...|.:||:::..:..|:||||.:|:|.:..:...:  .....|...:|
  Fly    87 LAESKFVHPTQVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHLFMNK--WSRTDGVGAII 149

  Fly   410 LVDCREAAVMVQREVLYYTNPLELRTHCLLGNSQWQGHA----ECDLLVASAGRLLQMIDNKKHV 470
            :...||.|..:...:.......:.....::|....:...    :|::|:.:.|||||.:| :..:
  Fly   150 ISPTRELAYQIFETLKKVGKHHDFSAGLIIGGKNLKFERTRMDQCNILICTPGRLLQHMD-ENPL 213

  Fly   471 VELERCTYLVLDNIDRMIDVGLEGNICRLLCRLRPHAQLIVSSTSWSSNLKRMANKFLGQYTAIR 535
            ........||||..||.:|:|.:..:..::....|..|.::.|.:.::.::.:|...|.....:.
  Fly   214 FNTSTMEMLVLDEADRCLDMGFQKTLNSIIENFPPVRQTLLFSATQTNTVQDLARLNLKDPVYVG 278

  Fly   536 VG-------------EINNIGVRL--QNIRQRVEVVNGLSKVERLMKELTAIYDTSDIPGKVVIY 585
            .|             :..|..|..  :.::|...|:|...|:..|..     :..:.:..|::::
  Fly   279 YGGATPREEPSASTKKTPNTAVLAVPELLQQSYVVLNLEDKITMLWS-----FIKNHLKQKIIVF 338

  Fly   586 V---KRQKVVEELVDLIRNCVPCEGIHGGRTAQENQGIIHDFGTGAYNIIVATQMTSNCLDVPGI 647
            |   |:.|.:.|:...:|...|...::|.........|..||...::.::.:|.:.|..||.|.:
  Fly   339 VASCKQAKYLYEIFCKLRPGSPLLALYGTLHQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPAV 403

  Fly   648 RYVINYDFPDNIDKYVQRMSRTGCLSYNRNCEVISFFTMANYKLVTEVVDFLKI---CKQEIGPH 709
            .:|:..|.|:::.:|:.|..|:........|.::...:...| :::.:.:.|.|   |
  Fly   404 NWVVQLDCPEDVSQYIHRAGRSARNKTRGECLLVLTPSEEEY-MISALKEQLNIDIRC------- 460

  Fly   710 LLQLAEEKMFGPR 722
             :|:..:|:|.||
  Fly   461 -VQIDPKKLFSPR 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14443	NP_572330.2	P-loop_NTPase	332..535	CDD:304359	42/206 (20%)
		DEXDc	345..544	CDD:214692	43/215 (20%)
		Helicase_C	560..670	CDD:278689	24/112 (21%)
CG5800	NP_573230.1	PRK01297	2..471	CDD:234938	88/465 (19%)
		DEADc	74..277	CDD:238167	42/205 (20%)
		HELICc	311..437	CDD:238034	27/130 (21%)
		DUF4217	474..530	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451444
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930