DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14443 and mahe

DIOPT Version :9

Sequence 1:NP_572330.2 Gene:CG14443 / 31595 FlyBaseID:FBgn0029880 Length:736 Species:Drosophila melanogaster
Sequence 2:NP_001284994.1 Gene:mahe / 31707 FlyBaseID:FBgn0029979 Length:945 Species:Drosophila melanogaster


Alignment Length:662 Identity:182/662 - (27%)
Similarity:312/662 - (47%) Gaps:119/662 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    87 SFSGPHSAGGFSKSTRESRSKSRSMG-----------NGKFRGKSHLRSSSESAHSSGSESSSSD 140
            :|.|  :|||...:...:.:.|...|           ||...|.:.....:.....:|...:.:.
  Fly    49 NFGG--AAGGAGINGAATAAGSMHFGQPYGVMTYGIQNGLGMGAAGSGGGNPYRQQNGVAFAGNG 111

  Fly   141 SNSGSSSDSDSTTGSSSHGSDTGERPRMRSAVFRIHETWQSPNSFKAVKTSRENKESRSRSSSLP 205
            ...|:...|.   ||..:|...|:.|...       :.:|.||:                     
  Fly   112 LGGGAGGGSG---GSGGYGGQRGKNPTYA-------QRYQKPNN--------------------- 145

  Fly   206 QKRFCPSKTQNDLTYGSPEPKSPSNRGRNSWRVGMRTPWKKSQSRSMSCSSIQKILVSRSFTRSR 270
                           |:.......:...|:..:||.:..::::        ||:       .:::
  Fly   146 ---------------GAGVAGGYQSNNYNAAALGMLSKEERAE--------IQR-------EKAK 180

  Fly   271 SPHRNTLCYQDQSKNPSRPSNYNTWKQPMDEVYNNAANYRKRHNITLTSWNMRNLPEPVLSFERS 335
            :|.||.:..:.::..|.....||.....:.:.....|..|:...||::.   ..||.||:|||.|
  Fly   181 NPGRNLVKPKWENLEPFLKDFYNIHPNTLAKSEQQVAEIRRELEITVSG---NELPHPVVSFEES 242

  Fly   336 GFNATILQQLEDQGYDGPTPIQAQTWSIAKEGKNIVMISGKGTGKTLGYLLPGIMKMHNQRGLMQ 400
            ...|.::::::.||:..||.||:|.|.||..|:::|.|:..|:||||.|:||.|:.:.||..:::
  Fly   243 SLPAHVIEEMKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPPIIR 307

  Fly   401 HKKGPIVLILVDCREAAVMVQ---REVLYYTNPLELRTHCLLGNSQWQGHAE-----CDLLVASA 457
             .:|||.|:|...||.|..:|   |:..:...| |:|..|:.|.|.....|.     .::::|:.
  Fly   308 -GEGPIALVLAPTRELAQQIQSVVRDYGHLCKP-EIRHTCIFGGSSKVPQARDLDRGVEVIIATP 370

  Fly   458 GRLLQMIDNKKHVVELERCTYLVLDNIDRMIDVGLEGNICRLLCRLRPHAQLIVSSTSWSSNLKR 522
            |||:..::|:.  ..|:||||||||..|||:|:|.|..|.:::.::||..|:::.|.:|...::.
  Fly   371 GRLIDFLENRN--TNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQVVMWSATWPKEVQA 433

  Fly   523 MANKFLGQYTAIRVGEIN---NIGVRLQNIRQRVEVVNGLSKVER---LMKELTAIYDTSDIPGK 581
            :|..||..|..|.:|.:|   |     .||||.||:...:.|.:|   |:.|::.|.::.:...|
  Fly   434 LAGDFLNDYIQINIGSMNLSAN-----HNIRQIVEICTEIEKPQRLVCLLNEISPIKNSGNNGNK 493

  Fly   582 VVIYVKRQKVVEELVDLIRNCVPCEG-----IHGGRTAQENQGIIHDFGTGAYNIIVATQMTSNC 641
            ::::|:.:..||:::.:||    .||     |||.:|..|...::.||..|..||::||.:.|..
  Fly   494 IIVFVETKIKVEDILQIIR----AEGYNATSIHGDKTQNERDSVLKDFRNGKSNILIATDVASRG 554

  Fly   642 LDVPGIRYVINYDFPDNIDKYVQRMSRTGCLSYNRNCEVI----SFFTMANYKLVTEVVDFLKIC 702
            |||..::||||||:|::.:.||.|:.|||      .|:.:    :|||..|.|...|::..|:..
  Fly   555 LDVEDLQYVINYDYPNSSENYVHRIGRTG------RCQQLGTAYTFFTPDNAKQARELISVLEEA 613

  Fly   703 KQEIGPHLLQLA 714
            .|.....||.||
  Fly   614 GQTPSQALLDLA 625

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14443NP_572330.2 P-loop_NTPase 332..535 CDD:304359 75/210 (36%)
DEXDc 345..544 CDD:214692 75/209 (36%)
Helicase_C 560..670 CDD:278689 40/117 (34%)
maheNP_001284994.1 PTZ00110 136..656 CDD:240273 164/570 (29%)
DEADc 239..446 CDD:238167 75/210 (36%)
HELICc 457..594 CDD:238034 49/146 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45445061
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0331
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR47958
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.840

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