Protein Alignment APC7 and anapc7

DIOPT Version :10

• Sequence 1: NP_572329.3
• Gene: APC7 / 31594
• FlyBaseID: FBgn0029879
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: NP_001107057.1
• Gene: anapc7 / 558402
• ZFINID: ZDB-GENE-081104-113
• Length: 566
• Species: Danio rerio
• Alignment Length: 559
• Identity: 146/559 - (26%)
• Similarity: 255/559 - (45%)
• Gaps: 37/559 - (6%)

  Fly    35 ADLLRTVLKNDRYVATLDVEYQVLLYLLNANYKERNYRAALRHFDEIIHKRRLMMR-------HK 92
            :.||.|:..|:..:.:...:||:|:|..:|.:.::.||.|...::..:.:::::.:       ..
Zfish    23 SSLLLTMSTNNPELFSPSQKYQLLVYHADAIFHDKEYRNAACKYNMALQQKKMLSKTSKVRPSST 87

  Fly    93 NAVLVAIES-SYPEFGDAEQRRRAAECYRQIGNTDMAIETLLQVPPTLRSPRINLMLARLQHHGS 156
            .:...|::: :.|  .:.|.:.:.||||..:.....||..|..:|...|:|:||:|||.|.....
Zfish    88 GSTTSAVQAQNLP--SEIEVKYKIAECYTILKLDKDAISVLDGIPSRQRTPKINMMLANLYRKAG 150

  Fly   157 RHGTTKKSEAVLAYKEVIRECPMALQVIEALLELGVNGNEINSLVMHAATVPDHFDWLSKWIKAL 221
                 ::..||.:||||:|:||:||..|..||.|.|.|.|:.|:.|.......:.||||.||||.
Zfish   151 -----QERSAVTSYKEVLRQCPLALDAIIGLLSLSVKGAEVASMTMDVIQSIPNLDWLSVWIKAH 210

  Fly   222 AQMFNFKHSDASQTFLMLHDNTTLRCNEHLMMALGKCLYYNGDYFQAEDIFSSTL------CANP 280
            |.:....:..|..|...|...:.||.|..|::.|...      ||:|.|..:|.|      ..:|
Zfish   211 AFIHGGDNQRAINTICSLEKKSLLRDNVDLLVTLADV------YFRAGDTKNSILKFEQAQMLDP 269

  Fly   281 DNVEAIGLMAVLCGQEGGCEQDSADMDYLFAKVSSEVKYTASHWFAHAQLLYDEGKFERGLNFVE 345
            ..::.:.:...|..:||..|    |::.|..::.:.....|..|.......:...::.|.|....
Zfish   270 YLIKGMDVYGYLMAREGHLE----DVEVLGGRLFNISDQHAEPWVISGCHSFYSKRYSRALYLGA 330

  Fly   346 KCLDSEPRNHEALILRGRLLIALERHTQAVCAFRTAQMVAPYRFEIYRGLFHSYLAQKRFKEANA 410
            |.:.....:.:||:|:|..|..:.|..:|:..||.|..:||.|.:.|.||...|||....:||..
Zfish   331 KAIQLNSNSVQALLLKGVALRNMGRVQEAIIHFREAMRLAPCRLDCYEGLIDCYLASNGIREAMG 395

  Fly   411 LCNWTIRLFQNSPRSFTMFGRTLFLFPDPRMRRTARKFAEKSLKINHIYTPAVNLIADICQVEGP 475
            :.|...:....:.::.|:.. |:.| .||..:..|:...:|:|.....|..||...|::...|..
Zfish   396 MANNIYKTLGANAQTLTILA-TVCL-EDPMTQEKAKTLLDKALAQRPDYIKAVVKKAELLSREQK 458

  Fly   476 TKAIIKLLEKHVIIFPKVNLLNHLGDIMRKQKEPVKAMEYYYKALRQDPKSKRTLRGLRLLAKSD 540
            .:..|.||...:.......|...|||.:....:..:||:.|..||..||..:::|.|::.:.|.:
Zfish   459 YEEGIALLRNTLANQSDCVLHRMLGDFLVAVNDYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEE 523

  Fly   541 DESPVLDESDDIGMDNQQSINDLTTLCEATNAQGAEGAE 579
            ..:....|.|...|:......||    |.::::.|:.|:
Zfish   524 SPTDATVELDGDDMEGSGEEGDL----EGSDSEAAQWAD 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APC7	NP_572329.3	CpoB	34..135	CDD:441335	22/107 (21%)
		LapB	108..411	CDD:442196	93/308 (30%)
		TPR repeat	251..277	CDD:276809	8/31 (26%)
		LapB	254..523	CDD:442196	66/274 (24%)
		TPR repeat	321..349	CDD:276809	5/27 (19%)
		TPR repeat	354..384	CDD:276809	10/29 (34%)
		TPR repeat	459..489	CDD:276809	8/29 (28%)
		TPR repeat	493..521	CDD:276809	8/27 (30%)
anapc7	NP_001107057.1	Spy	161..>421	CDD:443119	76/271 (28%)
		TPR repeat	238..266	CDD:276809	8/33 (24%)
		LapB	320..528	CDD:442196	55/209 (26%)
		TPR repeat	339..369	CDD:276809	10/29 (34%)
		TPR repeat	442..471	CDD:276809	8/28 (29%)
		TPR repeat	476..504	CDD:276809	8/27 (30%)