DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment APC7 and CG31687

DIOPT Version :9

Sequence 1:	NP_572329.3	Gene:	APC7 / 31594	FlyBaseID:	FBgn0029879	Length:	615	Species:	Drosophila melanogaster
Sequence 2:	NP_001163022.1	Gene:	CG31687 / 318886	FlyBaseID:	FBgn0051687	Length:	351	Species:	Drosophila melanogaster

Alignment Length:	299	Identity:	68/299 - (22%)
Similarity:	105/299 - (35%)	Gaps:	96/299 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 YLLNANYKERNYRAALRHFDEIIHKRRLMMRHKNAVLVAIESSYPEFGDAEQRRRAAECYRQIGN 124
            |.|..:|.:      :|.:|...|..|           ..|||.|.|........|.|..|....
  Fly    76 YFLAKSYYD------VREYDRAAHAVR-----------NCESSVPRFLHFYSSYMAREKRRLDST 123

  Fly   125 TDMAIETLLQVPPTLRSPRINLMLARLQHHGSR--------HGTTKK-------SEAVLAYKEVI 174
            ||.|   .|..|..:|.....|...|:::..||        :|...|       :|.:|.  :.|
  Fly   124 TDQA---NLHEPNQMRDLADLLATLRMEYGKSRLDGYGIYLYGVVLKALNLNQAAEQMLV--QAI 183

  Fly   175 RECPMALQVIEALLELGVNGNEINSLVMH-----AATVPDHFDWLSKWIKALAQMFNFKHSDASQ 234
            |..||   :..|.|||       :.|:|.     :..:..|  |:             :|...:.
  Fly   184 RLVPM---LWSAYLEL-------SPLIMEKKKLLSLQLGGH--WM-------------RHFFMAH 223

  Fly   235 TFLMLHDNTT-LRCNEHL-------------MMALGKCLYYN-GDYFQAEDIFSSTL-CANP--- 280
            |:|.|:.|.. |:..|.|             .|||   :|:| .|..:|.:::.:.| .|:|
  Fly   224 TYLELYLNDDGLKIYEDLQASGFSKSIYLIAQMAL---VYHNKRDVDKAIELYQALLESASPYRL 285

  Fly   281 DNVEAIGLMAVLCGQEGGCEQDSADMDYLFAKVSSEVKY 319
            |||:....:..:       ::...:|..|..|..|..||
  Fly   286 DNVDTYSNLLFV-------KEMKTEMAQLAHKAVSINKY 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
APC7	NP_572329.3	TPR repeat	251..277	CDD:276809	9/40 (23%)
		TPR_11	321..386	CDD:290150
		TPR repeat	321..349	CDD:276809
		TPR repeat	354..384	CDD:276809
		TPR_11	356..418	CDD:290150
		TPR repeat	459..489	CDD:276809
		TPR repeat	493..521	CDD:276809
CG31687	NP_001163022.1	ANAPC8	11..119	CDD:281973	14/59 (24%)
		TPR repeat	255..278	CDD:276809	7/25 (28%)
		TPR repeat	287..314	CDD:276809	5/33 (15%)
		TPR repeat	319..347	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930