Protein Alignment APC7 and APC7

DIOPT Version :10

• Sequence 1: NP_572329.3
• Gene: APC7 / 31594
• FlyBaseID: FBgn0029879
• Length: 615
• Species: Drosophila melanogaster
• Sequence 2: XP_308135.5
• Gene: APC7 / 1269494
• VectorBaseID: AGAMI1_009012
• Length: 585
• Species: Anopheles gambiae
• Alignment Length: 608
• Identity: 169/608 - (27%)
• Similarity: 293/608 - (48%)
• Gaps: 70/608 - (11%)

  Fly    15 LFANAKKLYDHKLYECVIPAADLLRTVLKNDRYVATLDVEYQVLLYLLNANYKERNYRAALRHFD 79
            ||...|.|:|::||......|:|:.::...:|...:....:..|:|...:.:.||.:|.|...:.
Mosquito     4 LFEQLKTLFDYELYSNAATLANLIISIYDTNRATLSPQEHFGTLVYYAESLFHERRFREAETIYR 68

  Fly    80 EIIHKRRLMMRHKNAVLVAIESSYPE----FGDAEQRRRAA------ECYRQIGNTDMAIETLLQ 134
            :.:..:||:.::|:........|.|.    ..:.|.:.:.|      :|||.      ||..|..
Mosquito    69 QALQLKRLLTKNKSPNCKTTAGSVPGPVDLQSEVELKYKTARCLIEMKCYRD------AIVLLQS 127

  Fly   135 VPPTLRSPRINLMLARLQHHGSRHGTTKKSEAVLAYKEVIRECPMALQVIEALLELGVNGNEINS 199
            :....|:|::|::|::|.|:   ||  .:..|:..||||::|||:|.:.||.||.|||.|.|:||
Mosquito   128 LALKQRTPKVNMLLSKLCHN---HG--HERSAIGTYKEVLKECPLAFEAIEGLLTLGVKGIEVNS 187

  Fly   200 LVMHAATVPDHFDWLSKWIKALAQMFNFKHSDASQTFLMLHDNTTLRCNEHLMMALGKCLYYNGD 264
            :::.|...|...:|:|.||||.|.:...|:::|.||...:..||.||....|::.:|:|.|:|||
Mosquito   188 MIVDATMAPQCSEWMSSWIKAHANIQARKYTEAIQTLRSIEANTCLRNYHQLLVLIGECYYHNGD 252

  Fly   265 YFQAEDIFSSTLCANPDNVEAIGLMAVLCGQEGGCEQDSADMDYLFAKVSSEV-KYTASHWFAHA 328
            |.||...........|.:...:.::|:|..:    .:..|:::.|.....|.: :||:..|:...
Mosquito   253 YEQAYITLKRAHAMQPQSKNGLQILALLMAK----NKKIAELEKLITPSPSLLNEYTSEMWYVMG 313

  Fly   329 QLLYDEGKFERGLNFVEKCLDSEPRNHEALILRGRLLIALERHTQAVCAFRTAQMVAPYRFEIYR 393
            |.|:..||:|:.:.||:|......||.|||:|:..:|..::::.|.:...|..|..||||:||::
Mosquito   314 QYLFATGKYEKAVYFVQKACFQNSRNVEALVLKAEVLFQVKKYQQGIAHLRYGQQFAPYRYEIHK 378

  Fly   394 GLFHSYLAQKRFKEANALCNWTIRLFQNSPRSFTMFGRTLFLFPDPRMRRTARKFAEKSLKINHI 458
            .|..:||...|.:||.......:::...|.|...:..||  ...|...|..|:....|:|:::..
Mosquito   379 ALVDNYLNMGRNREAQLQALKAVKMLGESARMLVLLART--YMKDEAARPKAKALCLKALEMSEN 441

  Fly   459 YTPAVNLIADICQVEGPTKAIIKLLEKHVIIFPKVNLLNHLGDIMRKQKEPVKAMEYYYKALRQD 523
            :.|||.|:::|...|......:|||:|||::.....|...|.:.:..:|:...|:|:|..||..|
Mosquito   442 FLPAVYLLSEIYLRENDISTRMKLLKKHVMLSKNSKLHVMLAETLNNEKDHSGALEHYSIALNLD 506

  Fly   524 PKSKRTLRGLRLLAKSDDESPVLDESDDIGMDNQQSINDLTTLCEATNAQGAEGAESVENSREAS 588
            |.::..:.||.::.::                                    :|..|     .::
Mosquito   507 PSNRVAMSGLLMVGQN------------------------------------KGGTS-----SSA 530

  Fly   589 SSAAARSGQEEDVDEHDWIDVPD 611
            |:|.|.|...|.:.| |..||||
Mosquito   531 SNAGASSSYLESMAE-DGSDVPD 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APC7	NP_572329.3	CpoB	34..135	CDD:441335	22/110 (20%)
		LapB	108..411	CDD:442196	102/309 (33%)
		TPR repeat	251..277	CDD:276809	10/25 (40%)
		LapB	254..523	CDD:442196	77/269 (29%)
		TPR repeat	321..349	CDD:276809	9/27 (33%)
		TPR repeat	354..384	CDD:276809	9/29 (31%)
		TPR repeat	459..489	CDD:276809	12/29 (41%)
		TPR repeat	493..521	CDD:276809	7/27 (26%)
APC7	XP_308135.5	None