DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pat1 and klc4

DIOPT Version :9

Sequence 1:	NP_001259286.1	Gene:	Pat1 / 31593	FlyBaseID:	FBgn0029878	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_001017813.1	Gene:	klc4 / 550511	ZFINID:	ZDB-GENE-050417-350	Length:	185	Species:	Danio rerio

Alignment Length:	171	Identity:	45/171 - (26%)
Similarity:	73/171 - (42%)	Gaps:	42/171 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 MNTKI-PALDRISRLAE----LPRNLLIDVYE-MMSQQESLKDTLLEELAQL--EVFARLVRYPF 89
            |:|.: |..:|:.:|.:    ....|:|...| :.|:..|:..:|||.:..|  :..|.||.
Zfish     1 MSTMVYPREERLEKLTQDEIISSTKLVIQGLEALKSEHNSILQSLLETIQCLKKDEEASLVH--- 62

  Fly    90 ARSQLLR-----IMASLMASQKMLA-------------------KRL-SENYVSRYEVV-AGHEE 128
            .:|.|||     |...|..:|.|:|                   :|| .||...|.|:. ..|:.
Zfish    63 EKSSLLRKSVEMIELGLGEAQVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQHKV 127

  Fly   129 EELESSMDTVED--RSTEF-SSLYTYDSESTNADSISDFND 166
            ::.|.|:..:|:  :..|| :.|..||..:|  ..:|..||
Zfish   128 QKSEQSVAQLEEEKKHLEFMNQLKKYDDGAT--PEVSPHND 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pat1	NP_001259286.1	DnaQ_like_exo	<53..110	CDD:299142	21/83 (25%)
		TPR_12	478..547	CDD:290160
		TPR_12	516..590	CDD:290160
		TPR_10	517..553	CDD:290111
		TPR repeat	518..546	CDD:276809
		TPR repeat	559..590	CDD:276809
		TPR repeat	603..628	CDD:276809
klc4	NP_001017813.1	SMC_prok_B	31..>145	CDD:274008	29/116 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910