DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pat1 and Klc1

DIOPT Version :9

Sequence 1:NP_001259286.1 Gene:Pat1 / 31593 FlyBaseID:FBgn0029878 Length:686 Species:Drosophila melanogaster
Sequence 2:XP_006240683.1 Gene:Klc1 / 171041 RGDID:621411 Length:615 Species:Rattus norvegicus


Alignment Length:545 Identity:112/545 - (20%)
Similarity:197/545 - (36%) Gaps:158/545 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 VYEMMSQQESLKDTLLEELAQLEVFARLVRYPFARSQLLRIMASLMASQKMLAKRLSENYVSRYE 121
            :::.||....:|:..||:|.|.|:.::                             ::..:...|
  Rat     1 MHDNMSTMVYMKEEKLEKLTQDEIISK-----------------------------TKQVIQGLE 36

  Fly   122 VVAGHEEEELESSMDTVEDRSTEFSSLYTYDSESTNADSISDFNDEFSADIGSIVGLPHRRATQE 186
            .:.......|:|.::|:               :....|..|:..:|.|:.|         |.:.|
  Rat    37 ALKNEHNSILQSLLETL---------------KCLKKDDESNLVEEKSSMI---------RKSLE 77

  Fly   187 ELDAINDSGLEELSAVELQVIDLGLRLGSFLSEAGWMQESITVLACLNVRLKDLPTHKHWLQFRL 251
            .|         ||...|.||:   :.|.:.|:.....::.      |..:::.|.....||:..|
  Rat    78 ML---------ELGLSEAQVM---MALSNHLNAVESEKQK------LRAQVRRLCQENQWLRDEL 124

  Fly   252 -DCLQRLLYAESAHCNFKEAEKTYAELMG-LNKWLNKSVPNQLVAITYSQISAM-----YFARNE 309
             :..|:|..:|.:....:| ||.:.|.|. |.|:.:...|::    .....|:.     .|..:|
  Rat   125 ANTQQKLQKSEQSVAQLEE-EKKHLEFMNQLKKYDDDISPSE----DKDSDSSKEPLDDLFPNDE 184

  Fly   310 ------YKNSHLWSGLAMRFLKGYANP---RTIIDVLRQAAKACVVKRDFARANLLICQAVRRAR 365
                  .:..|. |..|.....||..|   ||:.:::.|.|.    :..:..|..|..||:....
  Rat   185 DDPGQGIQQQHS-SAAAAAQQGGYEIPARLRTLHNLVIQYAS----QGRYEVAVPLCKQALEDLE 244

  Fly   366 EYFGPTHQKYGDALLDYGFFLLNVDS-VFQSVNIYKEALAVRRGIFGNMNFHVAIAHEDLSYAYY 429
            :..|..|.....        :||:.: |::..|.||:|        .|:          |:.|..
  Rat   245 KTSGHDHPDVAT--------MLNILALVYRDQNKYKDA--------ANL----------LNDALA 283

  Fly   430 VHEYSTGDFSCAQDHVDKAVNIMQHLVPSNHLMLASAKRVKALLLEEIALDKMADGIDEEDLLLQ 494
            :.|.:.|     :||...|..:       |:|.:...||.|                     ..:
  Rat   284 IREKTLG-----RDHPAVAATL-------NNLAVLYGKRGK---------------------YKE 315

  Fly   495 SEELHNFALLLSLQVFGEVNVQTAKHYGNLGRLYQTMNRFEEAERMHKKAIKIKSELLGHFDYEV 559
            :|.|...||.:..:|.|:.:...||...||..|.|...::||.|..:::|::|....||..|..|
  Rat   316 AEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNV 380

  Fly   560 GLSIGHLASLYNYQMKKYRDAEQLY 584
            ..:..:|||.| .:..|::.||.||
  Rat   381 AKTKNNLASCY-LKQGKFKQAETLY 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pat1NP_001259286.1 DnaQ_like_exo <53..110 CDD:299142 8/52 (15%)
TPR_12 478..547 CDD:290160 16/68 (24%)
TPR_12 516..590 CDD:290160 24/69 (35%)
TPR_10 517..553 CDD:290111 11/35 (31%)
TPR repeat 518..546 CDD:276809 10/27 (37%)
TPR repeat 559..590 CDD:276809 10/26 (38%)
TPR repeat 603..628 CDD:276809
Klc1XP_006240683.1 TPR_12 210..287 CDD:290160 21/106 (20%)
TPR_10 213..253 CDD:290111 10/43 (23%)
TPR repeat 214..241 CDD:276809 8/30 (27%)
TPR_12 251..329 CDD:290160 25/136 (18%)
TPR_10 254..294 CDD:290111 13/70 (19%)
TPR repeat 255..283 CDD:276809 10/53 (19%)
TPR_12 293..370 CDD:290160 24/104 (23%)
TPR_10 296..337 CDD:290111 12/68 (18%)
TPR repeat 297..325 CDD:276809 9/55 (16%)
TPR_12 335..413 CDD:290160 24/71 (34%)
TPR_10 338..379 CDD:290111 14/40 (35%)
TPR repeat 338..368 CDD:276809 10/29 (34%)
TPR_10 380..417 CDD:290111 10/26 (38%)
TPR repeat 381..408 CDD:276809 9/25 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1840
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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