Protein Alignment Pat1 and Klc2

DIOPT Version :10

• Sequence 1: NP_572328.1
• Gene: Pat1 / 31593
• FlyBaseID: FBgn0029878
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001356290.1
• Gene: Klc2 / 16594
• MGIID: 107953
• Length: 636
• Species: Mus musculus
• Alignment Length: 433
• Identity: 105/433 - (24%)
• Similarity: 168/433 - (38%)
• Gaps: 99/433 - (22%)

  Fly   185 QEELDAINDSGLEELSAVELQVI-DLGLRLGSFLSEAGWMQESITVLACLNVRLKDLPTHKHWLQ 248
            :..|:||      ||...|.||| .|...||:..||   .|:       |..:::.|.....||:
Mouse    62 RRSLEAI------ELGLGEAQVILALSSHLGAVESE---KQK-------LRAQVRRLVQENQWLR 110

  Fly   249 FRL-DCLQRLLYAESAHCNFKEAEKTYAELMGLNKWLNKSVPNQLVA-ITYSQISAMYFARNEYK 311
            ..| ...|:|..:|.|....:|.::....:..:.|....:.||:... :....:..::  .||.:
Mouse   111 EELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDSLDDLF--PNEDE 173

  Fly   312 NSHLWS---GLAMRFLKGYANP---RTIIDVLRQAAKACVVKRDFARANLLICQAVRRAREYFGP 370
            .|...|   |.......||..|   ||:.:::.|.|.    :..:..|..|..||:....:..|.
Mouse   174 QSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYAS----QGRYEVAVPLCKQALEDLEKTSGH 234

  Fly   371 THQKYGDALLDYGFFLLNVDS-VFQSVNIYKEALAVRRGIFGNMNFHVAIAHEDLSYAYYVHEYS 434
            .|.....        :||:.: |::..|.||:|                 ||. |:.|..:.|.:
Mouse   235 DHPDVAT--------MLNILALVYRDQNKYKDA-----------------AHL-LNDALAIREKT 273

  Fly   435 TGDFSCAQDHVDKAVNIMQHLVPSNHLMLASAKRVKALLLEEIALDKMADGIDEEDLLLQSEELH 499
            .|     :||...|..:       |:|.:...||.|                     ..::|.|.
Mouse   274 LG-----KDHPAVAATL-------NNLAVLYGKRGK---------------------YKEAEPLC 305

  Fly   500 NFALLLSLQVFGEVNVQTAKHYGNLGRLYQTMNRFEEAERMHKKAIKIKSELLGHFDYEVGLSIG 564
            ..||.:..:|.|:.:...||...||..|.|...:.||.|..:::|::|.:..||..|..|..:..
Mouse   306 KRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKN 370

  Fly   565 HLASLYNYQMKKYRDAEQLYMRSIDISLRL----FGNSYSGLE 603
            :|||.| .:..||:|||.||.   :|..|.    ||:..:.||
Mouse   371 NLASCY-LKQGKYQDAETLYK---EILTRAHEKEFGSVNARLE 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pat1	NP_572328.1	Spy	471..>628	CDD:443119	38/137 (28%)
		TPR_12	516..590	CDD:315987	26/73 (36%)
		TPR repeat	518..546	CDD:276809	10/27 (37%)
		TPR repeat	559..590	CDD:276809	12/30 (40%)
		TPR repeat	603..628	CDD:276809	1/1 (100%)
Klc2	NP_001356290.1	Crescentin	26..>132	CDD:437057	24/85 (28%)
		TPR	195..437	CDD:440225	70/282 (25%)
		TPR repeat	199..226	CDD:276809	8/30 (27%)
		TPR repeat	240..268	CDD:276809	11/53 (21%)
		TPR repeat	282..310	CDD:276809	9/55 (16%)
		TPR repeat	323..353	CDD:276809	10/29 (34%)
		TPR repeat	366..393	CDD:276809	11/30 (37%)