DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17717 and Marchf2

DIOPT Version :9

Sequence 1:	NP_572327.1	Gene:	CG17717 / 31592	FlyBaseID:	FBgn0029877	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_663461.2	Gene:	Marchf2 / 224703	MGIID:	1925915	Length:	287	Species:	Mus musculus

Alignment Length:	214	Identity:	51/214 - (23%)
Similarity:	87/214 - (40%)	Gaps:	37/214 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 CSSQ------IVASAHGTPTASTAALEISSARQRMLRSHLQESLHSANESGNSCRICRWNRNDME 102
            |||.      :.|:..|.|   ....:::|...|:| |.:..:|.|.::. ..||||....|...
Mouse    16 CSSSPAFSKVVEATGLGPP---QYVAQVTSRDGRLL-STVIRALDSQSDC-PFCRICHEGANGEN 75

  Fly   103 IIKCPCNCKGSVGYIHLKCLKRWIMHRRDNRCEICNAVFNIAEERASLKQMI---------RTFC 158
            ::. ||.|.|::|.:|..||::|:.....:.||:|:..|.:.:....|.:.:         ||.|
Mouse    76 LLS-PCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKRTLC 139

  Fly   159 CGRCCGLIVKHLLFSASLMPLAHIILQQVLQCMDNMNQGSTDQLTVQEVFVASCALLTSSALFFH 223
            |...|.:.:         .|||.|   ....|:    :|:.|.|.:.....|...:..:.|||..
Mouse   140 CDMVCFVFI---------TPLAAI---SGWLCL----RGAQDHLRLHSRLEAVGLIALTIALFTI 188

  Fly   224 FFEFVTTRFMLIRNILSHW 242
            :..:....|.....:.|.|
Mouse   189 YVLWTLVSFRYHCQLYSEW 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17717	NP_572327.1	RINGv	91..138	CDD:128983	16/46 (35%)
Marchf2	NP_663461.2	RINGv	63..110	CDD:128983	16/47 (34%)
Marchf2	NP_663461.2	Vpu	173..>224	CDD:109608	7/35 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000792
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46065
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.870