DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17717 and MARCHF8

DIOPT Version :9

Sequence 1:	NP_572327.1	Gene:	CG17717 / 31592	FlyBaseID:	FBgn0029877	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_001269795.1	Gene:	MARCHF8 / 220972	HGNCID:	23356	Length:	573	Species:	Homo sapiens

Alignment Length:	160	Identity:	41/160 - (25%)
Similarity:	63/160 - (39%)	Gaps:	43/160 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HHQHVLSEAAALRLINGLESAGNATMPLGAQPPQSAAAEAICSSQIVASAHGTPTA---STAALE 64
            |..|.| |:.|.||.....|:|            .|.:...||.::     |....   ||:|
Human   275 HRFHEL-ESCAARLHTAKSSSG------------LAGSMGFCSDEM-----GDDDVFEDSTSA-- 319

  Fly    65 ISSARQRMLRSHLQES------------------LHSANESGNSCRICRWNRNDMEIIKCPCNCK 111
              ..:.|:||:.|..:                  :...:.||:.||||....:|...:..||:|.
Human   320 --KLKSRVLRAPLCSTEKDSDLDCPSPFSEKLPPISPVSTSGDVCRICHCEGDDESPLITPCHCT 382

  Fly   112 GSVGYIHLKCLKRWIMHRRDNRCEICNAVF 141
            ||:.::|..||::||.......||:|...|
Human   383 GSLHFVHQACLQQWIKSSDTRCCELCKYEF 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17717	NP_572327.1	RINGv	91..138	CDD:128983	17/46 (37%)
MARCHF8	NP_001269795.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..72
MARCHF8	NP_001269795.1	RINGv	361..409	CDD:128983	17/47 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5397
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R328
SonicParanoid	1	1.000	-	-		X270
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.890