DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf128 and rnf128

DIOPT Version :9

Sequence 1:	NP_001166820.1	Gene:	Rnf128 / 315911	RGDID:	1566282	Length:	428	Species:	Rattus norvegicus
Sequence 2:	XP_012824820.2	Gene:	rnf128 / 100145171	XenbaseID:	XB-GENE-877067	Length:	403	Species:	Xenopus tropicalis

Alignment Length:	393	Identity:	236/393 - (60%)
Similarity:	292/393 - (74%)	Gaps:	19/393 - (4%)

- Green bases have known domain annotations that are detailed below.

  Rat    38 GAEAVWTAYLNVSWRVPHPGVNRTVWELSEEGVYGQDSPLEPVSGVLVPPDGPGALNACNPHTNF 102
            ||:.:|||.:|.|:...    |||..|..|.||:|||||:|..:|::|.|.......||..:|||
Frog    28 GADTLWTANVNYSYVYD----NRTYGEEGEIGVFGQDSPIERAAGLVVLPKSERTFTACKDNTNF 88

  Rat   103 TVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAGDIV 167
            :||..|..    .|:|||.|||||||.:||:.|.||||...|::| .|..|||..|||||..|.|
Frog    89 SVPHNWNG----PWIALILRGGGCTFTEKINRAAERGARAVVVYN-NGMDNEVFEMSHPGTKDTV 148

  Rat   168 AIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSAR 232
            ||||||:||.:|::.|:.|:||.||||||:|||.|:||||||||||||||:||||||||||||||
Frog   149 AIMIGNIKGNEIVEVIKGGMQVMMVIEVGRKHGSWINHYSIFFVSVSFFIVTAATVGYFIFYSAR 213

  Rat   233 RLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDVVRILTCNH 297
            |.|..|||::|.:||||:||||||:|||||:|||||.:||||||||||||.|||:||||||||||
Frog   214 RWRLTRAQNKKMKQLKAEAKKAIGKLQLRTIKQGDKVLGPDGDSCAVCIEPYKPSDVVRILTCNH 278

  Rat   298 IFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVP-VSNEAS-NTASPHEEDNRSE 360
            .|||.|:|||||||||||||||||||:|||..| |:.:.|..:| ||:|.. :|....||:||||
Frog   279 FFHKNCIDPWLLEHRTCPMCKCDILKSLGIAED-EEETTSAAIPSVSSELQRSTVQTIEEENRSE 342

  Rat   361 TASSGYASVQGADEPPLEEHAQSANENLQLVNHEANSVAVDVVPHVDNPTFEEDETPDQEMAVRE 425
            .||||||||:|.|||  .:..|...||.:||::||::.:::|:||||||.||     .:::.|.|
Frog   343 MASSGYASVRGGDEP--VDEGQHIYENTELVHNEASATSIEVLPHVDNPGFE-----SEDVHVHE 400

  Rat   426 VKS 428
            :||
Frog   401 MKS 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf128	NP_001166820.1	PA_GRAIL_like	48..193	CDD:239037	71/144 (49%)
Rnf128	NP_001166820.1	zf-RING_2	275..318	CDD:290367	37/42 (88%)
rnf128	XP_012824820.2	PA_GRAIL_like	38..174	CDD:239037	71/144 (49%)
		COG5540	<208..302	CDD:227827	76/93 (82%)
		RING-H2_RNF128_like	256..304	CDD:319716	42/47 (89%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I19507
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	426	1.000	Inparanoid score	I8280
OMA	1	1.010	-	-		QHG39235
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0011956
OrthoInspector	1	1.000	-	-		oto204510
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.080