Protein Alignment CG34417 and AIP5

DIOPT Version :9

• Sequence 1: NP_001259282.1
• Gene: CG34417 / 31591
• FlyBaseID: FBgn0085446
• Length: 5182
• Species: Drosophila melanogaster
• Sequence 2: NP_116671.1
• Gene: AIP5 / 850570
• SGDID: S000001912
• Length: 1233
• Species: Saccharomyces cerevisiae
• Alignment Length: 1493
• Identity: 271/1493 - (18%)
• Similarity: 482/1493 - (32%)
• Gaps: 463/1493 - (31%)

  Fly   869 TTTKPGDIFS-----LP-PTTPPTINNEPTLTTTRNTTTTTTTTTTA-------TSDNLQNHPKK 920
            :.|..||.:|     || |:|...|.:...||.:........|...|       .|..|:.|.||
Yeast    18 SVTSAGDSYSTLATDLPLPSTNDIIESRDQLTESDLDEAINATENFAQELSSQRKSSKLKGHKKK 82

  Fly   921 SAIEPATDTDSQPIRKVKLSANEAKVVEEAPCVRRQYYQLGNEGENPETPESSGTPANKKPHQMR 985
            :..:...:.|...|  ||||::..                       ||.|:|...|..  |.:.
Yeast    83 NQGQIKANRDRDTI--VKLSSSVG-----------------------ETEEASTRDAIS--HDLE 120

  Fly   986 RPHDEPE---PQLRRSSKSPSVEPRQVQRETTFEGRRVSQDREISIDELILIEETSG---APGSP 1044
            |..|..|   ..:..:::||:                     :|.||..::|:|||.   |.|:.
Yeast   121 RKDDVIEIATDTINDATESPT---------------------QIPIDVNVVIKETSTNNVAEGTE 164

  Fly  1045 KIPSPRAQSPG-----KPATRSQSPEKPQPRATPRQSPEKEQPAFKQTHEVYTPSQPEKQFPRAR 1104
            .:| |..:|.|     .|.||.:..:|  .:.|.|:......||  .|.::...|..:.......
Yeast   165 NVP-PIKESTGIEVGNSPITRRKKNKK--KKTTNRRGRNSSNPA--DTTDLSKQSTLDSILVGIE 224

  Fly  1105 SPEKTPGWTQPQVSPRQSPEKQLPRAQSPEKVPAVRQPSVSPRQSPEKQIPDPKTRDQGPGLPRI 1169
            ...:..|.....:                 ||..|:...|    :.||.  |.:||:
Yeast   225 EYLQEDGSKNEDI-----------------KVNIVQDEPV----NVEKM--DIRTRN-------- 258

  Fly  1170 SPRQSPEKQLPKDVPQKSRQSPEKDLTNQQRREEEIFRSTITTTQKRTTNNLNEEFITNERDNQN 1234
               :|.:|....|||.|                     ..:..|..::.||:|||...:....:.
Yeast   259 ---ESSDKTFDIDVPNK---------------------DNVDETSSKSENNINEEKAEHTLPREE 299

  Fly  1235 QPISEKKPQIPANAEPNTKPSETIESPDGGFPSKTTEVEAQP------EVKESPTYRKKGLTRRE 1293
            ..|........|:.:...:| ..:|:.|....:.|.:||::.      ..||:.:...|...:::
Yeast   300 NEILNVNEGNAASFKHQLEP-HGLEAGDENGQASTKDVESESLTKNGFNFKENESKHLKAGEKQQ 363

  Fly  1294 TFEDRCRQILGMEEDGDTQGTYTERPNNEQEDVNVSHTTIETIQVKIEDCPNDDEDDKPRRVTET 1358
            |..||         ||.:.....:  |.::.::.......|         ..|.||:|.|:
Yeast   364 TESDR---------DGISPSVLAK--NQKETEIGKEDHVFE---------QKDKEDEKCRK---- 404

  Fly  1359 YVVRTQPKIKVEEELFVDVTEAEDVEILVNPSKKSPKEEDSPKYPKGPETPKSPRNDQRIPSIPK 1423
                 :..:..|..:..:...|....|:...:::...::::    .|| |.:...|::.:    :
Yeast   405 -----ELSVNHENNMSHNFNAAGSDSIIPPETERETYDDET----MGP-TKRISDNEKNL----Q 455

  Fly  1424 KGQSPVQFKTEETPRYPQEQERYPKEPETSQYPKESPRNPKEDAETININE-------------- 1474
            .|.:.:..:.|      :|:|...:|.|.|.:.|....|...:.|.:..||
Yeast   456 HGTNDISVEVE------KEEEEEEEEEENSTFSKVKKENVTGEQEAVRNNEVSGTEEESTSKGEE 514

  Fly  1475 ------------ETTIVITKEGSKSPSPRWSP-----SPERRVPKSQQPPSPTASPSVSPVSGR- 1521
                        |.:.:|..|||.: |.:.|.     ..|...|..:..|:........|.:.|
Yeast   515 IMGGDEKQSEAGEKSSIIEIEGSAN-SAKISKDNLVLEDEAEAPTQENKPTEVVGEIDIPDAPRD 578

  Fly  1522 --KIPNEVESNFVTEKIIDCRGKTVVEKISQRPRTPSPTTPKKNTKPSQKIPERVPETESEPEKD 1584
              :|...||.|.:.|.:       .|.|..|.........|.|..| ..||..|..|:.||..|.
Yeast   579 DVEIVEAVEKNIIPEDL-------EVAKEDQEGEQVKLDEPVKAMK-DDKIAMRGAESISEDMKK 635

  Fly  1585 SESETKKTTSVSVTK--TETERRNSRTTKTKQPLPLKEPQSKVPAGKSPRKDSLTGRKRDSLVEE 1647
            .:..|.:.::....|  .||.|.::...:.:        :||.|......|...:||..|..:.|
Yeast   636 KQEGTAELSNEKAKKEVDETARESAEGVEVE--------KSKTPESPKVVKRCTSGRPEDLQINE 692

  Fly  1648 TRITTTTTTTRQGRKPSDTNGSPSIKDRLRSSPRKQKTSPQQTRTPTPAQTRNPEDDVDGDSSSP 1712
                         |.|.      .:|:                      ..|.|::||     .|
Yeast   693 -------------RDPE------VLKE----------------------DVRVPDEDV-----KP 711

  Fly  1713 DASPTRVGNERR--RSSNISVHTEIIIDHMAPKSPKTERRSQGGTGNVPSPIRKLPVTERKESAP 1775
            :.:.|...:|..  :|..:.:.||         ..:|.::..|..|:         .|..||...
Yeast   712 EIATTIENSEEEDPKSQRVQISTE---------QAETTQKDMGDVGS---------TTSFKEEEK 758

  Fly  1776 VPRVTRRDKAEKVTRSTSENIIKMSGTKPHPEMSSLKPGGDRSRPSKCCTTKTINLSEQRINTAT 1840
            ..|.....:.:|:|...:.          |....:.:...:.|:.|
Yeast   759 PKRFEITQEGDKITGKDTN----------HEHGEATEAASENSKAS------------------- 794

  Fly  1841 DIEGVIIDIQQAKSSREPSPDRI-VPTPVPAELETGKPRYPDVVQEPDDEPRRKPQVTNIPIFEE 1904
                   |:..|:...|||.:.: ..|...||:|.         .|..:..:.|.::.|:...:|
Yeast   795 -------DVGTAEKYIEPSSESVKKDTEEDAEVEN---------SEKTEFIKVKAELENLDAPKE 843

  Fly  1905 ESQTYVGCQISELHSSN-GIEVDILDNPTVEAPKSLDYPVNTPDTDESLLSVHEKVSRFTHSAEK 1968
            ...|      :||:..| .:|||..::..||..:..::               .||.....:.:.
Yeast   844 AEVT------AELNKENEDVEVDTEEDAEVENSEKTEF---------------IKVKAELGNLDA 887

  Fly  1969 VKEPKVSAPFSREFDVNAKIPENDDCLLSINQKVDKFLRTAENVIRPTSLPSRPEIERPGLEEID 2033
            .||.:|:|..::|                 |:.|:....:.|::....|.|:...||
Yeast   888 PKEAEVTAELNKE-----------------NEDVEVAATSKEDIETKCSEPAETPIE-------- 927

  Fly  2034 EELLRDDCTLSVSQKVHKFIDTAEKLAPTMPQKSPRLVANIERHISRQ-SEPERELDEESEPELD 2097
                ...||                                |..:|:: :|...:.||..|....
Yeast   928 ----DGTCT--------------------------------EAEVSKKDAEAVTKEDENMENSKI 956

  Fly  2098 RDT--DVEDDDQTSQLETEEEITQTV----TKKETLKEFKQQTK--ETRETRRDSKAEPEKLQKK 2154
            .:.  ||..|.:...:...:|..:||    .:|:.:|:.|.:.|  |..||.:::......:::.
Yeast   957 AEALKDVTGDQEIDDINISDEFQRTVELPELEKQDIKDNKGEDKELEVEETEKETSLPDLVVEEN 1021

  Fly  2155 SPQTK--VKEESARVPKYQAKVSQKVSQWEPKKQPQREPKVTQKETPLEPKKQPLS--------- 2208
            ..:.|  :|:|...|.:.....::.:|:..|...   |.....:.|...|||....
Yeast  1022 ITEEKNEIKQEEEEVSQLDFNETESISKEAPNND---ENGFEDQSTRENPKKASADDIFKDILDE 1083

  Fly  2209 --------KVKDEPEKVNKREPKVPQKESQTKLKEEPERVTKKTPQKEPRKEPLRQSEDEPEF 2263
                    |:.|:.| :|.....:..|:|.|:..|:.::...|........|..:.:|.||.:
Yeast  1084 TNEFLEQLKIVDDSE-LNALLQSLDAKDSTTQTTEQSKKNNDKPQDVITTSEIRKLNEKEPVY 1145

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34417	NP_001259282.1	Smoothelin	2594..2636	CDD:289290
		Smoothelin	3127..3176	CDD:289290
		GBP_C	<3810..3882	CDD:303769
		coiled coil	3857..3868	CDD:293879
		CH	5076..5179	CDD:237981
AIP5	NP_116671.1	2A1904	<271..>528	CDD:273344	49/322 (15%)
		PTZ00121	<482..1082	CDD:173412	141/810 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900