Protein Alignment CG34417 and specc1

DIOPT Version :10

• Sequence 1: NP_001259282.1
• Gene: CG34417 / 31591
• FlyBaseID: FBgn0085446
• Length: 5182
• Species: Drosophila melanogaster
• Sequence 2: XP_690827.4
• Gene: specc1 / 562343
• ZFINID: ZDB-GENE-060526-207
• Length: 1011
• Species: Danio rerio
• Alignment Length: 1259
• Identity: 257/1259 - (20%)
• Similarity: 420/1259 - (33%)
• Gaps: 393/1259 - (31%)

  Fly  4058 TSPIGLPWVAKPKVDNSDFRRKAHHFEERSLRDNIEQQQQPTYPNGNNGYLQRHNSLRSKAPALS 4122
            |:.:.||.:..|               ||:....|..|.  || :||.|.    .:.||.:...|
Zfish     6 TAKVALPRMGAP---------------ERAKLSTISSQS--TY-SGNIGM----KTSRSSSTIAS 48

  Fly  4123 EFK----KRPSLPNAMDP-------------GTAAPPRQVYQAPPPPTNISFTYADFPPVRR--P 4168
            :.:    ||.|..:|:..             .|.|........|...:::..|.....|..|  |
Zfish    49 DLRLSKIKRASSDDALAKPVLGSVSRIKKTITTGAIAELTDNRPRSASSVQSTKKSGIPAPREIP 113

  Fly  4169 QGASAHNYRSQPCLTSAVDQVEALTNPLGAPLVLTSSNPTYLPPPGSRRFDYISSPVDVDADSPP 4233
            |..|.....|:       ||.::.|    |..::|||:.:.:    |....:....|...|:|..
Zfish   114 QSISRERLSSR-------DQQKSST----AKKMVTSSSASSI----SALAKHSRGSVKTKAESAA 163

  Fly  4234 NSPTSFMTMPNPTLMTDNTDDDLDLDSDNNMLEYRAETKVMRKPRSQTAVRVADRRNAHMSDDEV 4298
            ...|.                   |:|....|...|:||.....:.:|.::      .|.
Zfish   164 LDKTL-------------------LESQVRELLAEAKTKEFEISKLRTELQ------RHK----- 198

  Fly  4299 YGKNSRAAKSLLYTMKQLGGGPGNASV--GNSGQRRQP-LTAPSSPKSGCLSPDGRPYQAPLVEP 4360
             ||:|                |..|..  |||...|.| ||.......|.|......:|.
Zfish   199 -GKDS----------------PSEAGTPEGNSEMERTPALTGDVQVLVGELREKNGRFQR----- 241

  Fly  4361 LFPQLSTFEPKRQP--------QFANSPMSTPPAVSMPSINYQANPTYTPPRSNQNSNSYLGETN 4417
               :|:|...:.|.        :.|:|...:...|...:||              .|......::
Zfish   242 ---ELATLREENQSLKQKLIALESASSSKHSVNGVVPDNIN--------------GSGLKTSVSS 289

  Fly  4418 TSYVVTYPLD--DSGDEPEPESMATSVSQRLRRTSEHSNASSSLSLGSTSWTANPVHNTVPS-VP 4479
            .|.:...||.  ||.:..:..|.:.|||..::                         :.||| |.
Zfish   290 ASDIKVSPLPSLDSSEFEKIPSRSDSVSSSIK-------------------------SVVPSGVV 329

  Fly  4480 LDSAMGPPVDRSTKPQVSQPVGPKMPQHVAQKQIP---QQLPNQLPQQIPQQLPKQ--------- 4532
            .|.::....:|..|.:.|        .|...:::.   |:|.:|  ||:.|:|..:
Zfish   330 KDLSVESLTERIQKMEES--------HHSTAEELQATLQELADQ--QQVVQELTAENERLAEEKG 384

  Fly  4533 -LPQQIPQQ------LPQQ---LPQQLPKQLPQQIP--------PQLPKQLPQQIPQP------- 4572
             |...:.||      |.||   |.|:|.:|...|..        .:|.::|.:|:...
Zfish   385 LLQTSLQQQRERVELLAQQNETLLQRLREQAQSQEAEASRASRMAELEQRLAEQVESSRFEREKL 449

  Fly  4573 -ELPQQLPNNLPRHAPKLSSRSHTIQGDSGYENRPLQNRVMSQQTLNSSII-------------- 4622
             ::.|||..:| |...|.:..:.|.......|...||..:.|::......:
Zfish   450 VDIQQQLTGSL-RALEKENQEAQTAVKSLREEEGLLQGHLESEKLARDEAVRKTEEQRLAMEALR 513

  Fly  4623 TSNNHTTVQKQQKEQHINELRRKSLGNVLESSQRSTYFEQEYKSSAPPDTPDI------VKSSLP 4681
            ..|.....|.:.:.|.:.||:      .::|:..:|..:...| .|..|...:      ::..|.
Zfish   514 VDNASMKAQVEVERQKVAELK------AVQSASDNTELQSLLK-VAHEDRDKLEMTCTELRQELQ 571

  Fly  4682 KEDA---PLLKKFGPPQRHHYMPNSYQSPQLNKQGNSNSTTTSSTSVRS------TTVVQQQHHQ 4737
            :.:|   .||:|....::.|             :.|:||....|....:      .|:.:.:...
Zfish   572 QVEADRQQLLEKVEKQEQDH-------------KANTNSLEEKSIDAENQIKDLKETIFELEDQV 623

  Fly  4738 QQHQQIKPSIVETPATPQPQVPP-ED---EIPHNI--------------------------VFNN 4772
            :|.:.::....:|....:.|:.. ||   |:...|                          |.|:
Zfish   624 EQQRAVRLHTNQTILDLENQIKKLEDNKTELEKQIKVVNKQMKDETEEWRRFQADLQTAVVVAND 688

  Fly  4773 VSA-----FTSMSRRNHEEDSHQGTQSGSRVNRLSKCDSWNQICQLQQTAGPSPAKYNQPGSPGE 4832
            :..     ..::.||..||..| ..:..|.:.::....|||:...|.          :..|||..
Zfish   689 IKVEAQQELRTLRRRLQEEQEH-SARLASELEQIQGTRSWNEDASLS----------DSDGSPHW 742

  Fly  4833 LRRTKSGHSLAVPKLYEAGIDKAQVSEKQRTVAAYFSGQKSPTGGQVEELRTSMTTTTSSRKSAI 4897
            .|.|.|.::.........|...:..||.:.|               |:.|..|..|.|.
Zfish   743 SRMTISQNAPVGFLTNGNGSGSSVSSEPEAT---------------VKSLIKSFDTATP------ 786

  Fly  4898 NRTKTSEKLSAAARKSLSSLTTTSNGNVSTAGLGMVVRGGGVGGIGGGAALSRS---ATMPHIAN 4959
            |.:.:|.::..:.|..||.:...:   ...|.:..:.|..|:..:  ...|.|.   ...||..:
Zfish   787 NGSSSSVQIHTSPRSPLSGIPVRT---APAAAVSPIQRHSGIKPL--SKTLERRIAFGDFPHNGS 846

  Fly  4960 LNLLDESNVEDAFEQLMMAQHKSSSSSEQRTETKSKDGGATVTTTTTKVTTRTVSGSAASKNISP 5024
            .:.|..|.       ||    :.|.|.|...:|.:...|.|.:.|..:..::.
Zfish   847 CDELKPST-------LM----RKSPSLESVIKTPAHFNGRTASFTYNRANSKL------------ 888

  Fly  5025 LAKFKQLDKQAAAQQAQKSSPTTSTPTTPGGSAQPLFKFTDPALNARAATVKDQLLQWCKHKTQE 5089
                          ..:::.|.::.....|||.                  ::.||:||:.||:.
Zfish   889 --------------SVERTDPLSALAREYGGSK------------------RNALLKWCQKKTEG 921

  Fly  5090 YENVQINNFSSSWSDGLAFCALIHHFLPDAFDYTTLTKQTRRHNFELAFSVADEKAGIAPLLDVE 5154
            |.|:.:.|||||||||||||||:|.:||....|..|..|.:..|..|||..| |..||.|.||.|
Zfish   922 YPNIDVTNFSSSWSDGLAFCALLHTYLPAHIPYQELISQDKGRNLTLAFQAA-ESIGIKPSLDFE 985

  Fly  5155 DMVEMSRPDWKCVFVYVQSIYRRF 5178
            :::...||||:.|..||..||:.|
Zfish   986 ELMRTDRPDWQSVMQYVSQIYKYF 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34417	NP_001259282.1	PHA03247	<566..1191	CDD:223021
		PTZ00449	<1035..1421	CDD:185628
		PTZ00449	<1394..1702	CDD:185628
		PTZ00121	<2080..2248	CDD:173412
		Smoothelin	2594..2636	CDD:463614
		Smoothelin	3127..3176	CDD:463614
		Smc	<3810..>3916	CDD:440809
		PHA03247	<4126..4601	CDD:223021	104/541 (19%)
		CH_SMTN-like	5074..5179	CDD:409049	51/105 (49%)
specc1	XP_690827.4	SMC_prok_B	<157..480	CDD:274008	81/427 (19%)
		PRK02224	<334..>719	CDD:179385	72/416 (17%)
		CH_SF	899..1010	CDD:469584	54/130 (42%)