DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34417 and smtnl1

DIOPT Version :9

Sequence 1:	NP_001259282.1	Gene:	CG34417 / 31591	FlyBaseID:	FBgn0085446	Length:	5182	Species:	Drosophila melanogaster
Sequence 2:	XP_005157270.1	Gene:	smtnl1 / 503743	ZFINID:	ZDB-GENE-050306-23	Length:	406	Species:	Danio rerio

Alignment Length:	349	Identity:	106/349 - (30%)
Similarity:	150/349 - (42%)	Gaps:	58/349 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  4853 DKAQVSEKQ-RTVAAYFSGQKSPTGG---------QVEELRTSMTTTTSSRKSAINRTKTSEKLS 4907
            :|..::|:: :...:.......|.||         :.||...:.|.....:......|.|.|:
Zfish    12 EKEVINEQESKHTESQEPADSEPRGGANKDNKENQEKEEAPANDTEACEQKGGVPENTNTVEE-- 74

  Fly  4908 AAARKSLSSLTTTSNGNVSTAGLGMVVRGGGVGGIGGGAALSRSATMPHIANLNLLDESNVEDAF 4972
                |....:|....|:|.........:.|.:...|     ..|:..|.....|..|:   |..|
Zfish    75 ----KEKQEITKNQTGDVEKETELNDNKEGEIKEEG-----KESSNDPPENENNSCDK---EGQF 127

  Fly  4973 EQLMMAQHKSSSSSEQRTETK--SKDGGATVTTTTTKVTTRTVSGSAASKNISPLAKFKQLDKQA 5035
            |:  ..:.|.:..:|.:||.|  .||             |:..|.....|..:|  ..|.....:
Zfish   128 EE--KQEEKRTKETECKTEKKEDEKD-------------TKQSSDEVKKKTENP--GRKNAAASS 175

  Fly  5036 AAQQAQKSSPTTSTPTTPGGSAQPLFKF----TDPALN----------ARAATVKDQLLQWCKHK 5086
            :|.:|...|..:|....|......:.||    |....|          |..|::|.::|.|||.|
Zfish   176 SALRASTKSSVSSRSARPSARRDAMAKFQKEETPGVRNFKVQRTSVGIAGGASIKQRILNWCKSK 240

  Fly  5087 TQEYENVQINNFSSSWSDGLAFCALIHHFLPDAFDYTTLTKQTRRHNFELAFSVADEKAGIAPLL 5151
            ||:||.|.|:|||||||||||||||:|.|.|.|||::||....|..||.||||.|:..|...|||
Zfish   241 TQKYEGVSIDNFSSSWSDGLAFCALVHRFFPSAFDFSTLKASEREKNFTLAFSTAETLADCCPLL 305

  Fly  5152 DVEDMVEMSR-PDWKCVFVYVQSI 5174
            :|.||:.|.: ||..|||.|||::
Zfish   306 EVSDMLLMGKNPDPLCVFTYVQAL 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34417	NP_001259282.1	Smoothelin	2594..2636	CDD:289290
		Smoothelin	3127..3176	CDD:289290
		GBP_C	<3810..3882	CDD:303769
		coiled coil	3857..3868	CDD:293879
		CH	5076..5179	CDD:237981	59/100 (59%)
smtnl1	XP_005157270.1	CH	233..329	CDD:214479	58/95 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4678
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001328
OrthoInspector	1	1.000	-	-		otm25181
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810