DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34417 and Muc18B

DIOPT Version :9

Sequence 1:	NP_001259282.1	Gene:	CG34417 / 31591	FlyBaseID:	FBgn0085446	Length:	5182	Species:	Drosophila melanogaster
Sequence 2:	NP_001285431.1	Gene:	Muc18B / 32913	FlyBaseID:	FBgn0031000	Length:	308	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	57/208 - (27%)
Similarity:	86/208 - (41%)	Gaps:	29/208 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   724 RAFAASLRSSSPADSTTSVGSHHQTPRSSVSSNRTFRREMREGSHD---SQAPSESSRISST--- 782
            |..|..:.|||.|....|:.:......|::.:.......:.|.:.:   ::||..:.::::.
  Fly    57 RCPAGLVFSSSMAQCVQSIAAFEARDDSNIENPTIPPSNLDESTTEKPATEAPGTTEKVTTAAPG 121

  Fly   783 TVTRHTTGGNVTSNTIKTK---TTKPVKTASEPRSPTPKAGGSVTTTTTTITTKSSPSPAPAS-- 842
            |..:.||....|:..|.|:   ||:.:.|  |....|.|.......||..|||:     ||.:
  Fly   122 TTEKVTTEAPGTTEKITTEAPGTTEKITT--EAPGTTEKITTEAPGTTEKITTE-----APGTTE 179

  Fly   843 -PTTAAP-PTSAPASSAPPDNKLSQYTYTTTKPGDIFSLPPTTPPTINNEP----TLTTTRNTTT 901
             |.|.|| .|..||:.||...:.|:   ||..||.........|  |.:||    |.|...||.|
  Fly   180 KPATDAPGTTEKPATDAPGTTEKSE---TTDAPGTTDKSDTDAP--ITDEPSTAETSTDEPNTET 239

  Fly   902 TTTTTTTATSDNL 914
            |.:...|...||:
  Fly   240 TESGEETTIEDNV 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34417	NP_001259282.1	Smoothelin	2594..2636	CDD:289290
		Smoothelin	3127..3176	CDD:289290
		GBP_C	<3810..3882	CDD:303769
		coiled coil	3857..3868	CDD:293879
		CH	5076..5179	CDD:237981
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884	6/14 (43%)
Muc18B	NP_001285431.1	MCLC	<77..177	CDD:283562	23/106 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900