Protein Alignment CG34417 and spdi

DIOPT Version :10

• Sequence 1: NP_001259282.1
• Gene: CG34417 / 31591
• FlyBaseID: FBgn0085446
• Length: 5182
• Species: Drosophila melanogaster
• Sequence 2: NP_001036254.1
• Gene: spdi / 31004
• FlyBaseID: FBgn0025633
• Length: 1094
• Species: Drosophila melanogaster
• Alignment Length: 1180
• Identity: 252/1180 - (21%)
• Similarity: 402/1180 - (34%)
• Gaps: 346/1180 - (29%)

  Fly  4244 NPTLMTDNTDDDLDLDSDNNMLEYRAETKVMRKPRSQTAVRVA-DRRNAHMSDDEVYGKNSRAAK 4307
            |.:..:.|:......:|.||.         .:|.:|.|::..| :::..|         :..||.
  Fly    14 NSSSHSSNSSHKQQQNSSNNN---------RQKSQSSTSLNTAHEQQQQH---------SITAAT 60

  Fly  4308 SLLYTMKQLGGGPGNASVGNSG----------QRRQPLTAPSSPKSGCLSPDGRPYQAPLVEPLF 4362
            :..|..::.........||:.|          ||||.......|:|..|.......:......|.
  Fly    61 TKFYAHQETASYERGVDVGDEGALLLTNQQQEQRRQQQQLLQQPQSNTLPQKKSKLKGQKQPKLL 125

  Fly  4363 PQLSTFEPKRQPQFANSPMSTPPAVSMPSINYQANPTYTPPRSNQNSNSYLGETNTSYVVTYPLD 4427
            |.........:|.....|:.|..| ::|    ||:.|.:...||.|:|:.|.          .|.
  Fly   126 PVQQPHSNAPEPHDPQQPLMTSLA-AVP----QASATGSSSNSNINNNNALA----------ALQ 175

  Fly  4428 DSGDEPEPESMATSVSQRLRRTSEHSNASSSLSLGSTSWTANPVHNTVPSVPLDSAMGPPVDRST 4492
            |.|   ...:.|....|:|...:. :.|:::.:.||.:...:|    |.|.|..:|
  Fly   176 DGG---AAAAAAADFYQQLAAAAT-ATATATSANGSNTSADSP----VSSFPAAAA--------- 223

  Fly  4493 KPQVSQPVGPKMPQHVAQKQIPQQLPNQLPQQIPQQLPKQLPQQIPQQLPQQLPQQLPKQLPQQI 4557
                :..|.........|:|..|||.|...||  |||.:      .....|:|.:|:.:...:|:
  Fly   224 ----AVAVAAVAASSYQQQQQQQQLLNNEQQQ--QQLLE------ANNKMQELHKQMERFRSEQM 276

  Fly  4558 PPQLPKQLPQQIPQPELPQQLPNNLPRHAPKLSSRSHTIQGDSGYENRPLQNRVMSQQTLNSSII 4622
              ||..::.:.:|......:|..:|.: ...|..:|....|:..|||..|:||:  :..:||.:.
  Fly   277 --QLETRITELLPYQSEVAKLKGDLVK-MQSLQEKSQMEIGNLKYENESLRNRL--RDVVNSPLS 336

  Fly  4623 TSNNHTTVQKQQK--------------------------------------------------EQ 4637
            .:..|..:|..|:                                                  |.
  Fly   337 DAEKHQIIQDSQRLHSSAPASIALPSTHDAHDGTPCLTPDWDKQSSSSEISVACLQDKIIQMEET 401

  Fly  4638 H--INELRRKSLGNVLE------------------------------------SSQRSTYFE--- 4661
            |  .||..:.:|..:.:                                    .:|.||..|
  Fly   402 HYSTNEELQATLQELADLQTQLTDTQTENERLAEEKDVLFQSLCRQTEKLNESRTQISTLQELLL 466

  Fly  4662 QEYKSSAPPDTP--------DIVKSSLPKEDAPLLKKFGPPQRHHYMPNSYQSPQLNKQGNSNST 4718
            ::.|..||..:.        |::|:|..:.:|.|||:.........|..:.::.||..|......
  Fly   467 RDTKQPAPEVSASEREQKLLDLIKTSQEEREAVLLKQEELGAELAEMKQAREAGQLELQRQRERI 531

  Fly  4719 TTSSTSVRSTTVVQQQHHQQQHQQIKPSIVETPATPQPQVPPEDEIPHN-IVFNNVSAFTSMSRR 4782
            ....:.:.:....::|...|..|.:                  :||... |..:.:|.....:|.
  Fly   532 ALLDSQLDAANAERRQGEAQFSQAM------------------EEISQRAIEISRLSTLLENARS 578

  Fly  4783 NHEE---DSHQGTQSGSR----VNRLSKCDSWNQICQLQQTAGPSPAKYNQ-----PGSPGELRR 4835
            ..||   |..:|.::...    |.|..|.....::.:||.....|.|:..:     .|...|.:.
  Fly   579 KIEELEADLSRGDKTDLSEVLDVARKEKDALEERVAELQDQCSRSQAELRRLRDQLSGLTEECKV 643

  Fly  4836 TKSGHSLAVPKL-YE-----------AG--------------------IDKAQ----VSEKQRTV 4864
            .|:....||..| |.           ||                    .||||    ::|.||.:
  Fly   644 VKNNAKCAVSHLEYRLEQLQRDKDKIAGEWQALEERVAELQVQCKCHQEDKAQLQSLLAETQRHL 708

  Fly  4865 AAYFSGQKSPTGGQVE-------ELRTS----------------------MTTTTSSRKSAINRT 4900
                 |......|:.|       :||..                      .|...|:|:..:...
  Fly   709 -----GDVQLKLGEAECRLDQETQLRRKEAEEWQQFQADLLMTVRVANDFKTEALSAREQLVLDN 768

  Fly  4901 KTSEKLSAAARKSLSSLTTTSNGNVST--AGLGMVVRGGGVGGIGGGAALSRSATMPHIANLNLL 4963
            ||.::......:.|..||........|  :.|..|.|...:.......:.||..:...:..|...
  Fly   769 KTQKEKIRLLEQQLEKLTKQQMQQSETPQSVLSTVQREMEMATRRSKLSFSRQDSRLSVKTLIES 833

  Fly  4964 DESNVEDAFEQLMMAQHKSSSSSEQRTETKSKDGGATVTTTTTKV-------------------- 5008
            .|:|         .||.|:..|....:.|.|.:.|.....||..:
  Fly   834 IENN---------KAQGKADESESHYSSTSSLNSGTPDLGTTPIIFPPSSDWHESIRLPVLQSTN 889

  Fly  5009 -------------TTRTVSGS-----AASKNISPLAKFKQLDKQAAAQQAQK-SSPTT-STPTTP 5053
                         .|.|.|||     :.:|...||...:||...:...|.|. |.|:| :||::.
  Fly   890 LHVNVGNEVGAGQGTNTSSGSGGDLASTTKATLPLRDQQQLAITSTQSQVQNVSQPSTPATPSSA 954

  Fly  5054 GGSAQPLFKF------------TDPALNARA---ATVKDQLLQWCKHKTQEYENVQINNFSSSWS 5103
            |.|:.....|            .|| ||..|   .:.::.||:||::||..|.|:.|.||||||:
  Fly   955 GSSSSGGLPFGNVSKSFISGERKDP-LNMLAKNGGSKRNALLKWCQNKTVGYRNIDITNFSSSWN 1018

  Fly  5104 DGLAFCALIHHFLPDAFDYTTLTKQTRRHNFELAFSVADEKAGIAPLLDVEDMVEMSRPDWKCVF 5168
            |||||||::|.:|||...|..||...:|.||.|||:.| |..||...|::.||.::.||||..|.
  Fly  1019 DGLAFCAILHSYLPDRIPYDQLTPANKRRNFSLAFAAA-ESVGIGTTLNINDMCQIERPDWMQVM 1082

  Fly  5169 VYVQSIYRRF 5178
            .||.::|:.|
  Fly  1083 SYVTAVYKYF 1092

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34417	NP_001259282.1	PHA03247	<566..1191	CDD:223021
		PTZ00449	<1035..1421	CDD:185628
		PTZ00449	<1394..1702	CDD:185628
		PTZ00121	<2080..2248	CDD:173412
		Smoothelin	2594..2636	CDD:463614
		Smoothelin	3127..3176	CDD:463614
		Smc	<3810..>3916	CDD:440809
		PHA03247	<4126..4601	CDD:223021	76/367 (21%)
		CH_SMTN-like	5074..5179	CDD:409049	51/105 (49%)
spdi	NP_001036254.1	SMC_prok_B	<257..>845	CDD:274008	106/624 (17%)
		Smc	<501..>794	CDD:440809	54/315 (17%)
		CH_CYTS	982..1093	CDD:409048	52/112 (46%)