DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spat and agxt

DIOPT Version :9

Sequence 1:	NP_511062.1	Gene:	Spat / 31587	FlyBaseID:	FBgn0014031	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001006705.1	Gene:	agxt / 448338	XenbaseID:	XB-GENE-950839	Length:	391	Species:	Xenopus tropicalis

Alignment Length:	379	Identity:	181/379 - (47%)
Similarity:	250/379 - (65%)	Gaps:	1/379 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VPPPLVLKRPLYVPSKTLMGPGPSNCSHRVLEAMSNPVLGHMHPECLQIMDEVKEGIKYIFQTLN 67
            :|||..|.:||.||.:.::||||||...|:..|.:..::||||||..||||::|:||:|.|||.|
Frog     7 IPPPSALLQPLNVPQRLMLGPGPSNVPPRIQAAGALQLIGHMHPEMFQIMDDIKQGIRYAFQTQN 71

  Fly    68 DATMCISGAGHSGMEAALCNLIEDGDVVLMGITGVWGHRAGDMARRYGAEVHYVEASFGRALSHE 132
            :.|:.:||:||..||.|:.|::|.|||||:.:.|:||.||||:|.|.||:|.||....|...:.:
Frog    72 NLTLAVSGSGHCAMETAIFNVVEKGDVVLIAVKGIWGERAGDIAERIGADVRYVSKPVGEGFTLK 136

  Fly   133 EITFAFEAHRPKVFFIAQGDSSTGIIQQNIRELGELCRKYDCFLIVDTVASLGGTEFLMDEWKVD 197
            |:..|...|:|.:|||..|:||:|::|. :..||:||.:|:|.|:||:||||||....||:..:|
Frog   137 EVEKALVEHKPSLFFITHGESSSGVVQP-LDGLGDLCHRYNCLLLVDSVASLGGAPIYMDKQGID 200

  Fly   198 VAYTGSQKSLGGPAGLTPISFSKRALTRIRKRKTKPKVYYFDILLIGQYWGCYGTPRIYHHTISS 262
            :.|:||||.|..|.|..|||||:.|..:|..|||||...|.|:..:..||||.|.|||||||...
Frog   201 ILYSGSQKVLNAPPGTAPISFSETASKKIFSRKTKPPSLYVDLKWLANYWGCDGKPRIYHHTGPV 265

  Fly   263 TLLYGLREALAHFCAVGLKAVVRRHQECSKRLQLGIEELGLEMFVSREEERLPTVNTIKVPFGVD 327
            |..:.|||.||.....||:.....|||.:.:|..|:|.|||::||.....|||||.|:.||.|.:
Frog   266 TNFFSLREGLAVLAEQGLERSWAVHQENALKLHKGLEALGLKLFVKDPALRLPTVTTVSVPNGYE 330

  Fly   328 WKKVAEYAMRKYSVEISGGLGPTVEHVFRIGLMGENATVERVDMVLSILNEAIQ 381
            |:.:..:.|:.:::||:|||||:...|.||||||.|:|...||.||..|.:|:|
Frog   331 WRDITTFIMKNHAIEITGGLGPSTGKVLRIGLMGYNSTQANVDRVLEALRDALQ 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spat	NP_511062.1	PucG	16..389	CDD:223153	174/366 (48%)
Spat	NP_511062.1	AGAT_like	19..381	CDD:99744	172/361 (48%)
agxt	NP_001006705.1	PucG	22..383	CDD:223153	171/361 (47%)
agxt	NP_001006705.1	AGAT_like	23..384	CDD:99744	172/361 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	336	1.000	Domainoid score	I1121
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37251
Inparanoid	1	1.050	379	1.000	Inparanoid score	I2024
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289834at33208
OrthoFinder	1	1.000	-	-		FOG0003987
OrthoInspector	1	1.000	-	-		oto105055
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2022
SonicParanoid	1	1.000	-	-		X3850
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090