Protein Alignment Agxt and AGXT

DIOPT Version :10

• Sequence 1: NP_511062.1
• Gene: Agxt / 31587
• FlyBaseID: FBgn0014031
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_000021.1
• Gene: AGXT / 189
• HGNCID: 341
• Length: 392
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 173/379 - (45%)
• Similarity: 238/379 - (62%)
• Gaps: 1/379 - (0%)

  Fly     3 VPPPLVLKRPLYVPSKTLMGPGPSNCSHRVLEAMSNPVLGHMHPECLQIMDEVKEGIKYIFQTLN 67
            |.||..|.:||.:|::.|:||||||...|::.|....::|.|..:..|||||:||||:|:|||.|
Human     8 VTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRN 72

  Fly    68 DATMCISGAGHSGMEAALCNLIEDGDVVLMGITGVWGHRAGDMARRYGAEVHYVEASFGRALSHE 132
            ..|:.|||:||..:||||.|::|.||..|:|..|:||.||.|:..|.||.||.:....|...:.:
Human    73 PLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQ 137

  Fly   133 EITFAFEAHRPKVFFIAQGDSSTGIIQQNIRELGELCRKYDCFLIVDTVASLGGTEFLMDEWKVD 197
            |:......|:|.:.|:..|:||||::|. :...||||.:|.|.|:||:|||||||...||...:|
Human   138 EVEEGLAQHKPVLLFLTHGESSTGVLQP-LDGFGELCHRYKCLLLVDSVASLGGTPLYMDRQGID 201

  Fly   198 VAYTGSQKSLGGPAGLTPISFSKRALTRIRKRKTKPKVYYFDILLIGQYWGCYGTPRIYHHTISS 262
            :.|:||||:|..|.|.:.||||.:|..::..|||||..:|.||..:..:|||...||:|||||..
Human   202 ILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPV 266

  Fly   263 TLLYGLREALAHFCAVGLKAVVRRHQECSKRLQLGIEELGLEMFVSREEERLPTVNTIKVPFGVD 327
            ..||.|||:||.....||:...|:|:|.:..|...::.|||::||.....|||||.|:.||.|.|
Human   267 ISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYD 331

  Fly   328 WKKVAEYAMRKYSVEISGGLGPTVEHVFRIGLMGENATVERVDMVLSILNEAIQ 381
            |:.:..|.:..:.:||.|||||:...|.||||:|.|||.|.||.|...|..|:|
Human   332 WRDIVSYVIDHFDIEIMGGLGPSTGKVLRIGLLGCNATRENVDRVTEALRAALQ 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agxt	NP_511062.1	AGAT_like	19..381	CDD:99744	165/361 (46%)
AGXT	NP_000021.1	AGAT_like	24..385	CDD:99744	165/361 (46%)