DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spat and Agxt

DIOPT Version :9

Sequence 1:	NP_511062.1	Gene:	Spat / 31587	FlyBaseID:	FBgn0014031	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_057911.2	Gene:	Agxt / 11611	MGIID:	1329033	Length:	414	Species:	Mus musculus

Alignment Length:	379	Identity:	180/379 - (47%)
Similarity:	245/379 - (64%)	Gaps:	1/379 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VPPPLVLKRPLYVPSKTLMGPGPSNCSHRVLEAMSNPVLGHMHPECLQIMDEVKEGIKYIFQTLN 67
            ||||..|.:||.||::.|:||||||.:.|||.|.|..::|||..|.||||:|:|:||:|:|||.|
Mouse    30 VPPPEALSKPLSVPTRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMLQIMEEIKQGIQYVFQTRN 94

  Fly    68 DATMCISGAGHSGMEAALCNLIEDGDVVLMGITGVWGHRAGDMARRYGAEVHYVEASFGRALSHE 132
            ..|:.:||:||..||.||.||:|.||..|.|..|:||.||.::|.|.||.||.:....|...:.:
Mouse    95 PLTLVVSGSGHCAMETALFNLLEPGDSFLTGTNGIWGMRAAEIADRIGARVHQMIKKPGEHYTLQ 159

  Fly   133 EITFAFEAHRPKVFFIAQGDSSTGIIQQNIRELGELCRKYDCFLIVDTVASLGGTEFLMDEWKVD 197
            |:......|:|.:.|:..|:||||::|. :...||||.:|.|.|:||:||||||....||:..:|
Mouse   160 EVEEGLAQHKPVLLFLVHGESSTGVVQP-LDGFGELCHRYQCLLLVDSVASLGGVPIYMDQQGID 223

  Fly   198 VAYTGSQKSLGGPAGLTPISFSKRALTRIRKRKTKPKVYYFDILLIGQYWGCYGTPRIYHHTISS 262
            :.|:.|||.|..|.|::.|||:.:|..::..|||||..:|.||..:.:.|||.|..|:.|||...
Mouse   224 IMYSSSQKVLNAPPGISLISFNDKAKYKVYSRKTKPVSFYTDITYLAKLWGCEGETRVIHHTTPV 288

  Fly   263 TLLYGLREALAHFCAVGLKAVVRRHQECSKRLQLGIEELGLEMFVSREEERLPTVNTIKVPFGVD 327
            |.||.|||:||.....||:...|||:|.:..|...::|:||:.||...|.||||:.|:.||.|.:
Mouse   289 TSLYCLRESLALIAEQGLENCWRRHREATAHLHKHLQEMGLKFFVKDPEIRLPTITTVTVPAGYN 353

  Fly   328 WKKVAEYAMRKYSVEISGGLGPTVEHVFRIGLMGENATVERVDMVLSILNEAIQ 381
            |:.:..|.:..:|:|||||||||.|.|.||||:|.|||.|.||.|...|.||:|
Mouse   354 WRDIVSYVLDHFSIEISGGLGPTEERVLRIGLLGYNATTENVDRVAEALREALQ 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spat	NP_511062.1	PucG	16..389	CDD:223153	172/366 (47%)
Spat	NP_511062.1	AGAT_like	19..381	CDD:99744	170/361 (47%)
Agxt	NP_057911.2	PucG	43..406	CDD:223153	170/363 (47%)
		AGAT_like	46..407	CDD:99744	170/361 (47%)
		Microbody targeting signal. /evidence=ECO:0000250	412..414
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850843
Domainoid	1	1.000	336	1.000	Domainoid score	I1113
eggNOG	1	0.900	-	-		E1_COG0075
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37251
Inparanoid	1	1.050	365	1.000	Inparanoid score	I2146
Isobase	1	0.950	-	0	Normalized mean entropy	S2200
OMA	1	1.010	-	-		QHG61020
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003987
OrthoInspector	1	1.000	-	-		oto94856
orthoMCL	1	0.900	-	-		OOG6_100588
Panther	1	1.100	-	-	LDO	PTHR21152
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2022
SonicParanoid	1	1.000	-	-		X3850
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740