DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3342 and GOLGA8H

DIOPT Version :9

Sequence 1:	NP_572324.1	Gene:	CG3342 / 31586	FlyBaseID:	FBgn0029874	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001269419.1	Gene:	GOLGA8H / 728498	HGNCID:	37443	Length:	632	Species:	Homo sapiens

Alignment Length:	278	Identity:	51/278 - (18%)
Similarity:	108/278 - (38%)	Gaps:	79/278 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 SKIRTKATVTKTTPNPPQPQPRSRVT-------------LPTLEKADDEERE--------RETET 239
            :|.:.|....|.:|..|....|:|.|             .|..:.|....||        ::.|:
Human    13 AKKKLKEYWQKNSPRVPAGANRNRKTNGSVPEKATSGGCQPPGDSATGFHREGPTSSATLKDLES 77

  Fly   240 PSNEDVIVTPVPRPIGSSNAHRKLSASSLAVANASTSSDTPLAVTTLDKYLDEQRASGALMEHKM 304
            |..|..:|               |.:.|:.::....:.          |.|.:|:..   :||::
Human    78 PCQERAVV---------------LDSRSVEISQLKNTI----------KSLKQQKKQ---VEHQL 114

  Fly   305 DAILQAMNRMGGQSSVAPKKPSDPLLERDSEDEMLELEQKLLNLKR-----ENRALMRNLKAREQ 364
            :...:|.|:                  :.....:||::.:.||:::     :...:.|:|:..|:
Human   115 EEEKKANNK------------------KQKAKRVLEVQIQTLNIQKGKLNTDLYHMKRSLRYFEE 161

  Fly   365 ALEDLRCSACALC-EELLVQNGELKSQNAQLLLASQHISDSSTAASPAHCR-NCESSSRQIAKMQ 427
            ..:||     |:| :..|.:.|||:|..:.::...:..::..::.|.|... ..|.|.|:.|.::
Human   162 KSKDL-----AVCLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREEALLK 221

  Fly   428 LHISALQEALRIFQKSGD 445
            :.::.|:|:.:..|...|
Human   222 VQLTQLKESFQQVQLERD 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3342	NP_572324.1	None
GOLGA8H	NP_001269419.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..77		12/63 (19%)
		DUF342	<175..291	CDD:302792	14/65 (22%)
		GOLGA2L5	226..621	CDD:291729	4/14 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	352..379
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	423..452
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	496..524
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900