DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3342 and GOLGA6L6

DIOPT Version :9

Sequence 1:	NP_572324.1	Gene:	CG3342 / 31586	FlyBaseID:	FBgn0029874	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001138476.2	Gene:	GOLGA6L6 / 727832	HGNCID:	37225	Length:	724	Species:	Homo sapiens

Alignment Length:	276	Identity:	54/276 - (19%)
Similarity:	95/276 - (34%)	Gaps:	94/276 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 LPVEHYLSEISSSSSASPSREDLSKIRTKATVTKTTPNPPQPQPRSRVTLPTLEKADDEERERET 237
            ||....:|:.:..|..:.::|.|            |.:.||       |.|::..|..:.::::.
Human    33 LPTHPMMSKETRQSKLAEAKEQL------------TDHHPQ-------TNPSVGTAASDTKKKKI 78

  Fly   238 ETPSNEDVIVTPVPRPIGSSNAH-----------------RKLSASSLAVANASTSSDTPL---- 281
            ...:|        |....|...|                 |:|.| .:......|...|.|
Human    79 NNGTN--------PETTTSGGCHSPEDEQKASHQHQEALRRELEA-QVHTIRILTCQKTELQMAL 134

  Fly   282 -----AVTTLD--------KYLDEQRASGALMEHKMDAILQAMNRMGGQSSVAPKKPSDPLLERD 333
                 ||..|:        :..|..:.:|.|.        ||::.:..|...|.:...:...|||
Human   135 YYSQHAVKQLEGEARDLISRLHDSWKFAGELE--------QALSAVATQKKKADRYIEELTKERD 191

  Fly   334 S----------EDEML-----ELEQKLLNLKRENRALMRNLKAREQALE---------DLRCSAC 374
            :          .||.|     ||::||..::.|...:..|:|..::.||         .|:..|.
Human   192 ALSLELYRNTITDEELKEKNAELQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD 256

  Fly   375 ALCEELLVQNGELKSQ 390
            .|.:||...:.:|::|
Human   257 HLGKELQSVSAKLQAQ 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3342	NP_572324.1	None
GOLGA6L6	NP_001138476.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..108		16/101 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	314..342
		TPH	367..713	CDD:290579
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	374..454
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..548
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	561..724
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900