DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3342 and GOLGA6L4

DIOPT Version :9

Sequence 1:	NP_572324.1	Gene:	CG3342 / 31586	FlyBaseID:	FBgn0029874	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001254465.2	Gene:	GOLGA6L4 / 643707	HGNCID:	27256	Length:	574	Species:	Homo sapiens

Alignment Length:	316	Identity:	60/316 - (18%)
Similarity:	112/316 - (35%)	Gaps:	45/316 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 RFDKEP--DEKEFITFMVKNKLPVEHYLSEISSSSSASPSREDLSKIRTKATVTKTTPNPPQP-- 214
            ||...|  .||.....:...|..::.|....|....|..:|:  .||...:..|.|:.....|
Human     6 RFPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGANRK--KKINGSSPDTATSGGYHSPGD 68

  Fly   215 -----QPRSRVTLPTLEKADDEERERETETPSNEDVI------VTPVPRPIGSSNAH-----RKL 263
                 ....|.:..|||..:.:.:|......|:..:|      :..:.|.......|     :||
Human    69 SATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKL 133

  Fly   264 SASSLAVANAST---SSDTPLAVTTLDKYLDEQRASGALMEHKMDAI---LQAMNRMGGQSSVAP 322
            ..|...:.|.:.   :.:.|...:.:::..||...    :..:::::   |||........|:..
Human   134 GRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNH----LRKELESVGRQLQAEVENNQMLSLLN 194

  Fly   323 KKPSDPLLE-----RDSEDEMLELEQKLLNLKRENRALMRNLKAREQALEDLRCSACALCEELLV 382
            ::..:.|.|     |:.|:.:.|.|.:|...:...|.....|..:|:.|.:.....|...|.|..
Human   195 RRQEERLREQEERLREQEERLREQEDRLHEQEERLREQEERLCEQEERLREHEERLCEQEERLCE 259

  Fly   383 QNGELKSQNAQLLLASQHISDSSTAASPAHCRNCESSSRQIAKMQLHISALQEALR 438
            |...|:.|..:|....:.:.:...       |.||...| :.:.:..:...:|.||
Human   260 QEERLREQEERLHEQEERLREQEE-------RLCEQEER-LREQEERLCEQEERLR 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3342	NP_572324.1	None
GOLGA6L4	NP_001254465.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..77		15/72 (21%)
		GOLGA2L5	83..>194	CDD:291729	19/114 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	491..552
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900