DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3342 and GOLGA8N

DIOPT Version :9

Sequence 1:	NP_572324.1	Gene:	CG3342 / 31586	FlyBaseID:	FBgn0029874	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001269423.1	Gene:	GOLGA8N / 643699	HGNCID:	44405	Length:	632	Species:	Homo sapiens

Alignment Length:	370	Identity:	63/370 - (17%)
Similarity:	130/370 - (35%)	Gaps:	119/370 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 LSEISSSSSASPSREDLSKIR----TKATVTKTTPNPPQPQ-----------PRSRVTLPTLEKA 228
            :.|.::|....|..:..:...    |.:...|...:|.|.:           .|.:.|:.:|::.
Human    42 IPETATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSTSVKISRLKNTIKSLKQQ 106

  Fly   229 DDE-ERERETETPSNEDVIVTPVPRPIGSSNAHRKLSA--SSLAVANASTSSDTPLAVTTLDKYL 290
            ..: |.:.|.|..:|.:           ...|.|:|..  .:|.:.....::|......:| :|.
Human   107 KKQVEHQLEEEKKANNE-----------RQKAERELEVQIQTLIIQKEELNTDLYHMERSL-RYF 159

  Fly   291 DEQRASGAL-----------MEHKMDAILQAMNRMGGQSSVAPKKPSDPLLERDSEDE------- 337
            :|:....|:           :|..:.|::....:...|.|...|..::..||:..:|:
Human   160 EEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQL 224

  Fly   338 -------------------------------MLELEQKLLNLKRENRALMRNLKAREQALEDLRC 371
                                           |.::.|::..||:|.:..||.::..|::|..|:.
Human   225 TQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSLSKLKN 289

  Fly   372 SAC--------ALCEELLVQN---------GELKSQNAQLLLASQHISDSSTAASPAHCRNCESS 419
            ...        |:..|:.:|:         |||:||    :..:||||..:        |..|..
Human   290 QMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQ----VKNNQHISLLN--------RRQEER 342

  Fly   420 SRQ----IAKMQLHISALQEALR-------IFQKSGDSSSSSGRL 453
            .|:    :.|.:..:....|.||       :|::..:.:.|:.:|
Human   343 IREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3342	NP_572324.1	None
GOLGA8N	NP_001269423.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..76		5/33 (15%)
		GOLGA2L5	226..622	CDD:291729	32/174 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	423..445
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	505..524
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	552..573
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900