DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3342 and GOLGA6B

DIOPT Version :9

Sequence 1:	NP_572324.1	Gene:	CG3342 / 31586	FlyBaseID:	FBgn0029874	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_061122.4	Gene:	GOLGA6B / 55889	HGNCID:	32205	Length:	693	Species:	Homo sapiens

Alignment Length:	473	Identity:	86/473 - (18%)
Similarity:	158/473 - (33%)	Gaps:	108/473 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DQSYQDFFDKLRSESGPRNLRQIFEDDDRPLANESSSLRYQPGSSKKLQAGKRPA-MTRSS---- 65
            |..||:....|  ||....:.|:.|:.: .|..:...:.:|...:||.......| |.|..
Human    68 DSQYQELAVAL--ESSSVTISQLNENIE-SLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINI 129

  Fly    66 -TQETGDSPPAAWNTAIAKVVHAYRSSENVGRVGLALSILGEMEAS------------------K 111
             |.|..|.....::|..|.......|.:..||:..:|..:.|:|.:                  :
Human   130 LTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCRE 194

  Fly   112 LIVYRSKSQVLT--------TLQLTPRGGKVIL-RESYLQFYDDEQRFWSLRFDKEPDEKEFITF 167
            .:::|...|.:.        ..|:|....:|.| |:.|.:....|:..|..|..|...|..  |.
Human   195 AVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEAR--TL 257

  Fly   168 MVKNKLPVEHYLSEISSSSSASPSREDLSKIRTKATVTKTTPNPPQPQPRSRVTLPTLEKADDEE 232
            ..:.|..: |.:.|:..|         ||:::.:..      .||...|.:..::  :|:..||.
Human   258 KEEKKRDI-HRIQELERS---------LSELKNQMA------KPPSLAPPAVTSV--VEQLQDEA 304

  Fly   233 RERETETPSNEDVIVTPVPRPIGSSNAHRKLSASSLAVANASTSSDTPLAVTTLDKYLDEQRASG 297
            :....|....|..:.:.|                                         |...:.
Human   305 KHLRQEVEGLEGKLQSQV-----------------------------------------ENNQAL 328

  Fly   298 ALMEHKMDAILQAMNRMGGQSSVAPKKPSDPLLERDSEDEMLELEQKLL-----NLKRENRALMR 357
            :|:..:....||....|..:..|...:..:.|.|   ::|.|..:||.|     .|:::.:.|.:
Human   329 SLLSKEQKQRLQEQEEMLREQEVQRVREQERLCE---QNERLREQQKTLQEQGERLRKQEQRLRK 390

  Fly   358 ---NLKAREQALEDLRCSACALCEELLVQNGELKSQNAQLLLASQHISDSSTAASPAHCRNCESS 419
               .|:..|:.|:..........|.|..:...|:.|..:|.|:..|..|...|.......:..:.
Human   391 QEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNE 455

  Fly   420 SRQIAKMQLHISALQEAL 437
            .:...:::..:..|||.|
Human   456 KKSALQLEQQVKELQEKL 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3342	NP_572324.1	None
GOLGA6B	NP_061122.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..72		1/3 (33%)
		GOLGA2L5	217..686	CDD:291729	58/321 (18%)
		V_ATPase_I	264..>346	CDD:279793	18/140 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	497..551
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	629..650
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	660..679
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900