DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3342 and Fkbp15

DIOPT Version :9

Sequence 1:	NP_572324.1	Gene:	CG3342 / 31586	FlyBaseID:	FBgn0029874	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	XP_006538097.1	Gene:	Fkbp15 / 338355	MGIID:	2444782	Length:	1255	Species:	Mus musculus

Alignment Length:	562	Identity:	108/562 - (19%)
Similarity:	189/562 - (33%)	Gaps:	182/562 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DQSYQDFFDKLRSESGPRNLRQIFEDDDRPLANESSSLRY----QPGSSKKLQAGKRPAMTRSST 66
            |:...||.    |.||...|..:|..|...:.:.:...:|    ||...:...||.:.| .:.:.
Mouse     6 DEDDTDFL----SPSGGAKLASLFGLDQATMGHGNEFFQYTAPKQPKKGQGTAAGNQTA-PKPAP 65

  Fly    67 QETGDSPPAAWNTAIAKVVHAYR----SSENVGRVGLALSILGEMEAS--KLIVYRSKSQVLTTL 125
            ..||.|     :...|..|||||    .....|:.|.|  :||...:.  ::::|.|:.|.:|..
Mouse    66 ATTGTS-----SVLFATAVHAYRYINGQYAKQGKFGAA--VLGNHTSREYRILLYISQQQPVTVA 123

  Fly   126 QLTPRGGKVILRESYLQFYDDEQRFWSLRFDKEPDEKEFITFMVKNKLPVEHYLSEISS------ 184
            .:......::...:|..||||:::.||:.|:   .||..::|   ||.......:.|||
Mouse   124 TIHLNFELMVRPNNYSTFYDDQRQNWSIMFE---SEKAAVSF---NKQVCVAKCNSISSLDAVLC 182

  Fly   185 ---SSSASPSREDLSKIRTKAT-----------VTKTTPNPPQP--------------------- 214
               .::..|:.|....:....|           |..:|.|..:|
Mouse   183 QDLVAAEGPAVETGDSLEVAYTGWLLQNHVLGQVFDSTANKDKPLRLKLGSGKVVKGLEDGLLGM 247

  Fly   215 -------------------------QPRSRVTLPTLEK-----ADDEERE------RETETPS-- 241
                                     ||...:.:..:|.     |.|...:      |::..||
Mouse   248 KKGGKRLIITPSACAAGSEGVIGWTQPTDSILVFEVEVRRVKFARDSGSDGHSVSSRDSAAPSPI 312

  Fly   242 ------NEDVIVTPVPRPIGSSNAHRKLSASSLA-VANASTSSDT-----------------PLA 282
                  :.|.:|||:|.|:.......:..::||: ....:::.||                 |:.
Mouse   313 PASDSLSADPVVTPLPLPLKPGEPGLRSKSNSLSEQLTVNSNPDTVKAKLISRMAKMGQPMLPIL 377

  Fly   283 VTTLDKYLDEQRASGALMEHKMDAILQAMNRMGGQSSVAPK-----KPSDPLLERDSEDEMLELE 342
            ...||....|...:..|             |..|||.|.|.     :|:.|:|.:.:.
Mouse   378 PPQLDSNDSETEDATVL-------------RGAGQSLVTPSIQPSLQPAHPVLPQMAS------- 422

  Fly   343 QKLLNLKRENRALMRNLKAREQALEDLRCSACALCEELLVQNGELKSQNAQLLLASQHISDSSTA 407
                             :|.:.:...|:..:.||.:.:.:.:....|.|||.......:...:..
Mouse   423 -----------------QAPQPSGSGLQTPSAALMQAVSLDSHSAVSGNAQNFQPYAGVQAYAYP 470

  Fly   408 ASPAHCRNCESSSRQIAKMQ-LHISALQEALRIFQKSGDSSS 448
            .:|       |.:.|:..:: |:.:.|.:|.. ||.|||..|
Mouse   471 QTP-------SVTSQLQPVRPLYPAPLSQAPH-FQGSGDMMS 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3342	NP_572324.1	None
Fkbp15	XP_006538097.1	FKBP_C	192..285	CDD:365980	8/92 (9%)
		PRK10263	<378..>489	CDD:236669	25/154 (16%)
		Smc	<561..890	CDD:224117
		PHA03247	<944..1129	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810