DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3342 and GOLGA6L2

DIOPT Version :9

Sequence 1:	NP_572324.1	Gene:	CG3342 / 31586	FlyBaseID:	FBgn0029874	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	NP_001291317.1	Gene:	GOLGA6L2 / 283685	HGNCID:	26695	Length:	909	Species:	Homo sapiens

Alignment Length:	284	Identity:	57/284 - (20%)
Similarity:	109/284 - (38%)	Gaps:	64/284 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 LPVEHYLSEISSSSSASPSRE--------DLSKIRTKATVTK-------TTP--------NPPQP 214
            ||....:||.:..:..:.:::        :::.:.|:||.||       |.|        :.|:.
Human     7 LPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPED 71

  Fly   215 QPRSRVTLPTLEKADDEERE---RETETPSNEDVIVTPVPRPIG-----SSNAHRKL-------- 263
            ..::|..|...:||..:.:|   ||.|...:...|:|.....:.     |.:|.||.
Human    72 TQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGTP 136

  Fly   264 SASSLAVANASTSSDTPLAVTTLDKYLDEQRASGALMEHK---MDAILQAMNRMGGQSSVAPKKP 325
            |:.:||::.|...|  ||...:......|.:.....:.|.   ...:.:|::.:......|.:..
Human   137 SSFNLALSQAFRGS--PLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYI 199

  Fly   326 SDPLLERD-----------SEDEM----LELEQKLLNLKRENRALMRNLKAREQALEDLR----- 370
            .:...|||           :.:|:    .||::||...:.|...:..|:|..::.||..:
Human   200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQ 264

  Fly   371 CSACALCEELLVQNGELKSQNAQL 394
            .....|.||:..|..||:.|..::
Human   265 VQTNTLQEEMWRQEEELREQEKKI 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3342	NP_572324.1	None
GOLGA6L2	NP_001291317.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..88		16/80 (20%)
		Neuromodulin_N	<193..444	CDD:331332	21/96 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..362
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..408
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	425..494
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..909
		Rho	540..>730	CDD:333130
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900