DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpV and PPH22

DIOPT Version :9

Sequence 1:	NP_001259272.1	Gene:	PpV / 31582	FlyBaseID:	FBgn0003139	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_010093.1	Gene:	PPH22 / 851339	SGDID:	S000002347	Length:	377	Species:	Saccharomyces cerevisiae

Alignment Length:	307	Identity:	158/307 - (51%)
Similarity:	221/307 - (71%)	Gaps:	8/307 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGDVDKWIEDVKKCKYLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRT 65
            :..:|:|||.:.||:.|.|:::.:||:|..|:|..|.|:.|::.|||:|||:||||:||.:||:.
Yeast    75 INQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKI 139

  Fly    66 GGQVPHTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSK 130
            ||..|.|||:||||:|||||||:||.:.|:.:|.|||.|||:||||||:||||:||||:|||..|
Yeast   140 GGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRK 204

  Fly   131 YGNANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWS 195
            ||:||.||....:||...:.|::|.::.|:||||||.|.|:||:|.::|..|:|::|..|||:||
Yeast   205 YGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWS 269

  Fly   196 DPEDMEYWGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGKLVTVWSAPNYC 260
            ||:|...||.||||||:.||.::::.|...|:|:||.||||||.||..:.....:||::||||||
Yeast   270 DPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYC 334

  Fly   261 YRCGNVAAILSFETAEKRQTKIFL----AVPDAERVIPKQNTTPYFL 303
            |||||.|||:..:....||   ||    :|...|..:.:: |..|||
Yeast   335 YRCGNQAAIMEVDENHNRQ---FLQYDPSVRPGEPTVTRK-TPDYFL 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpV	NP_001259272.1	PTZ00239	3..303	CDD:173488	156/303 (51%)
PpV	NP_001259272.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	152/287 (53%)
PPH22	NP_010093.1	MPP_PP2A_PP4_PP6	78..360	CDD:277360	152/284 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820