Protein Alignment PpV and PPP2CA

DIOPT Version :10

• Sequence 1: NP_511061.1
• Gene: PpV / 31582
• FlyBaseID: FBgn0003139
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_002706.1
• Gene: PPP2CA / 5515
• HGNCID: 9299
• Length: 309
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 164/301 - (54%)
• Similarity: 214/301 - (71%)
• Gaps: 0/301 - (0%)

  Fly     3 DVDKWIEDVKKCKYLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRTGG 67
            ::|:|||.:.:||.|.|:::|.|||...:||.:|:|:..|..|||||||:||||:||.:|||.||
Human     9 ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGG 73

  Fly    68 QVPHTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYG 132
            :.|.|||:||||:|||||||:||.|.|:.||.||..|||:||||||:||||:||||:|||..|||
Human    74 KSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYG 138

  Fly   133 NANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWSDP 197
            |||.|||...:||.|.:.|::|.::.|:||||||.|.|||.||.:||..|:|::|..|||:||||
Human   139 NANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP 203

  Fly   198 EDMEYWGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGKLVTVWSAPNYCYR 262
            :|...||.||||||:.||.::::.|...|.|.|:.||||||.||..:..|..:||::||||||||
Human   204 DDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYR 268

  Fly   263 CGNVAAILSFETAEKRQTKIFLAVPDAERVIPKQNTTPYFL 303
            |||.|||:..:...|.....|...|........:.|..|||
Human   269 CGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PpV	NP_511061.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	159/283 (56%)
PPP2CA	NP_002706.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	159/283 (56%)