Protein Alignment PpV and PPP1CB

DIOPT Version :10

• Sequence 1: NP_511061.1
• Gene: PpV / 31582
• FlyBaseID: FBgn0003139
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_002700.1
• Gene: PPP1CB / 5500
• HGNCID: 9282
• Length: 327
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 126/318 - (39%)
• Similarity: 188/318 - (59%)
• Gaps: 21/318 - (6%)

  Fly     3 DVDKWIE---DVKKCK-----YLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDL 59
            :||..|.   :|:.|:     .:.|.|::.||....:|.|.:..:|.:..|:.:|||||||:.||
Human     7 NVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDL 71

  Fly    60 EQLFRTGGQVPHTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFF 124
            .:||..||..|..||:|:||:||||..||||...||..|.:||....|||||||...|.::|||:
Human    72 LRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFY 136

  Fly   125 DECFSKYGNANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAF 189
            |||..:: |...||.....|:.|.||||:||::.|.||||||::.:::|||.|.|..::|..|..
Human   137 DECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLL 200

  Fly   190 CDLVWSDPE-DMEYWGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGKLVTV 253
            |||:||||: |::.||::.||..:.||.:|...|:..::|:|||||||:|.:|.::....:|||:
Human   201 CDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTL 265

  Fly   254 WSAPNYCYRCGNVAAILS-----------FETAEKRQTKIFLAVPDAERVIPKQNTTP 300
            :||||||....|...::|           .:.:||:....:..:.....|.|.:...|
Human   266 FSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANP 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PpV	NP_511061.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	123/303 (41%)
PPP1CB	NP_002700.1	MPP_PP1_PPKL	7..297	CDD:277359	121/290 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..327		3/19 (16%)