Protein Alignment PpV and PPP1CA

DIOPT Version :10

• Sequence 1: NP_511061.1
• Gene: PpV / 31582
• FlyBaseID: FBgn0003139
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 128/297 - (43%)
• Similarity: 186/297 - (62%)
• Gaps: 16/297 - (5%)

  Fly    17 LPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRTGGQVPHTNYIFMGDFV 81
            |.|||::.||....:|.|.:..:|.:..|:.:|||||||:|||.:||..||..|.:||:|:||:|
Human    41 LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYV 105

  Fly    82 DRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYGNANGWKYCCKVFDL 146
            |||..||||...||..|.:||....|||||||...|.::|||:|||..:| |...||.....|:.
Human   106 DRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNC 169

  Fly   147 LTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWSDPE-DMEYWGQSPRGA 210
            |.||||:||::.|.||||||::.:::|||.|.|..::|.:|..|||:||||: |::.||::.||.
Human   170 LPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGV 234

  Fly   211 GWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGKLVTVWSAPNYCYRCGNVAAILS---- 271
            .:.||..|...|:..::|:|||||||:|.:|.::....:|||::||||||....|..|::|
Human   235 SFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDET 299

  Fly   272 -------FETAEKRQTKI--FLAV-PDAERVIPKQNT 298
                   .:.|:|.:.|.  |..: |....:.|.:|:
Human   300 LMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNS 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PpV	NP_511061.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	125/284 (44%)
PPP1CA	NP_001008709.1	MPP_PP1_PPKL	8..309	CDD:277359	121/268 (45%)