DRSC/TRiP Functional Genomics Resources

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Protein Alignment PpV and PPEF2

DIOPT Version :9

Sequence 1:NP_001259272.1 Gene:PpV / 31582 FlyBaseID:FBgn0003139 Length:303 Species:Drosophila melanogaster
Sequence 2:NP_006230.2 Gene:PPEF2 / 5470 HGNCID:9244 Length:753 Species:Homo sapiens


Alignment Length:363 Identity:93/363 - (25%)
Similarity:135/363 - (37%) Gaps:132/363 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 LLEETNILPVST----PVTVCGDIHGQFYDLEQLF-RTGGQVPHTNYIFMGDFVDRGYYSLETFT 92
            |::..||..|||    .:|||||:|||..||..:| :.|...|..:|:|.|||||||..|:|...
Human   157 LVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILM 221

  Fly    93 RLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYGNANG---WKYCCKVFDLLTIAAIID 154
            .|......||....|.|||||...:...|||..|..:|| ..:|   .:....||..|.:|.:||
Human   222 ILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKY-KVHGKEILRTLQDVFCWLPLATLID 285

  Fly   155 EEVLCVHGGLS--PEIITLDQI------------------------------------------- 174
            |:||.:|||:|  .::..||:|                                           
Human   286 EKVLILHGGVSDITDLELLDKIERSKIVSTMRCKTRQKSEKQMEEKRRANQKSSAQGPIPWFLPE 350

  Fly   175 ----------------RTIDRNGEIPYKGAF-------------------C-------------- 190
                            :...|:..||..|:.                   |              
Human   351 SRSLPSSPLRLGSYKAQKTSRSSSIPCSGSLDGRELSRQVRSSVELELERCRQQAGLLVTGEKEE 415

  Fly   191 ---------------------------DLVWSDPEDME-YWGQSPRGAGWLFGHNVTKDFMAINN 227
                                       |::||||...| ....:.||.|..||.:||:..:...|
Human   416 PSRSASEADSEAGELRKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYN 480

  Fly   228 LNLICRAHQLVNEGIKYMFDGKLVTVWSAPNYCYRCGN 265
            :..:.|:|:...||.::..:.|::|::||.|| |..|:
Human   481 MQFLIRSHECKPEGYEFCHNRKVLTIFSASNY-YEVGS 517

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PpVNP_001259272.1 PTZ00239 3..303 CDD:173488 93/363 (26%)
MPP_PP2A_PP4_PP6 3..287 CDD:277360 93/363 (26%)
PPEF2NP_006230.2 MPP_RdgC 122..537 CDD:277364 93/363 (26%)
Catalytic 128..540 93/363 (26%)
PP2Ac 141..540 CDD:197547 93/363 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..382 4/63 (6%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 409..435 0/25 (0%)
EFh 657..722 CDD:238008
EF-hand_7 657..721 CDD:290234
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 732..753
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000018
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.900

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