DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpV and ppe1

DIOPT Version :9

Sequence 1:	NP_001259272.1	Gene:	PpV / 31582	FlyBaseID:	FBgn0003139	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_588420.1	Gene:	ppe1 / 2538758	PomBaseID:	SPCC1739.12	Length:	305	Species:	Schizosaccharomyces pombe

Alignment Length:	305	Identity:	206/305 - (67%)
Similarity:	251/305 - (82%)	Gaps:	2/305 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGDVDKWIEDVKKCKYLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRT 65
            |.|:|:||..|:|||||||::||:|||||..||:||:||.||.||||||||||||||||.:|||.
pombe     1 MFDLDEWIATVRKCKYLPEHQLKRLCEMVKVILMEESNIQPVRTPVTVCGDIHGQFYDLLELFRV 65

  Fly    66 GGQVPHTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSK 130
            ||::|.||||||||||||||:||||||..:.||||||.:|||||||||:||||:||||:|||.:|
pombe    66 GGELPSTNYIFMGDFVDRGYFSLETFTLFMLLKARYPDKITLLRGNHESRQITQVYGFYDECQTK 130

  Fly   131 YGNANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWS 195
            |||||.|||||:|||.||:||:||.::||||||||||:.||||||.:.|..|||::|:||||:||
pombe   131 YGNANVWKYCCQVFDFLTLAAVIDNKILCVHGGLSPEVRTLDQIRILARAQEIPHEGSFCDLMWS 195

  Fly   196 DPEDMEYWGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMF-DGKLVTVWSAPNY 259
            ||||:|.|..||||||||||..||.:|..||:|.||.||||||.||.||.| |..||||||||||
pombe   196 DPEDIESWTVSPRGAGWLFGSKVTTEFSQINDLTLIARAHQLVQEGYKYHFADKNLVTVWSAPNY 260

  Fly   260 CYRCGNVAAILSFETAEKRQTKIFLAVPDAERVI-PKQNTTPYFL 303
            ||||||||:::..:.:.:.:.:||.||.|.:|.: |.:..:.||:
pombe   261 CYRCGNVASVMKVDESLEPEFRIFSAVADEDRTVPPSRKRSEYFI 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpV	NP_001259272.1	PTZ00239	3..303	CDD:173488	204/301 (68%)
PpV	NP_001259272.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	199/284 (70%)
ppe1	NP_588420.1	PTZ00239	3..296	CDD:173488	202/292 (69%)
ppe1	NP_588420.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	198/283 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	315	1.000	Domainoid score	I239
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68273
Inparanoid	1	1.050	443	1.000	Inparanoid score	I307
OMA	1	1.010	-	-		QHG53795
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	1	1.000	-	-		oto101366
orthoMCL	1	0.900	-	-		OOG6_103044
Panther	1	1.100	-	-	LDO	PTHR45619
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R960
SonicParanoid	1	1.000	-	-		X2805
TreeFam	1	0.960	-	-
	13	12.950