DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpV and pph-4.1

DIOPT Version :9

Sequence 1:	NP_001259272.1	Gene:	PpV / 31582	FlyBaseID:	FBgn0003139	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_499603.1	Gene:	pph-4.1 / 176657	WormBaseID:	WBGene00004085	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	178/303 - (58%)
Similarity:	228/303 - (75%)	Gaps:	2/303 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DVDKWIEDVKKCKYLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRTGG 67
            |:|:.||.:.:|:.:.|.::|.||....:||.||.|:..:.:|||:|||||||||||.:||:.||
Worm    31 DLDRHIEKLMRCELIAEQDVKTLCAKAREILAEEGNVQVIDSPVTICGDIHGQFYDLMELFKVGG 95

  Fly    68 QVPHTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYG 132
            .||:|||:|:|||||||:||:|||..||.||||||.|:.|:|||||:||||:||||:|||..|||
Worm    96 PVPNTNYLFLGDFVDRGFYSVETFLLLLALKARYPDRMMLIRGNHESRQITQVYGFYDECLRKYG 160

  Fly   133 NANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWSDP 197
            ||:.||:|.:|||.|::||:||.:|.||||||||.|.|:||||.|||..|:|:.|..|||:||||
Worm   161 NASVWKHCTEVFDYLSLAAVIDGKVFCVHGGLSPSISTMDQIRVIDRKQEVPHDGPMCDLLWSDP 225

  Fly   198 EDMEY-WGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGKLVTVWSAPNYCY 261
            |:... ||.||||||:|||.:.:|.|...|.::|||||||||.||.|:.|:.|::||||||||||
Worm   226 EEGNVGWGLSPRGAGYLFGADASKTFCETNGVDLICRAHQLVMEGYKWHFNEKVLTVWSAPNYCY 290

  Fly   262 RCGNVAAILSFETAEKRQTKIFLAVPDAERVIP-KQNTTPYFL 303
            |||||||||..:....::..||.|.|...|..| |:....|||
Worm   291 RCGNVAAILELDENLNKEFTIFEAAPQENRGAPAKKPHADYFL 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpV	NP_001259272.1	PTZ00239	3..303	CDD:173488	176/301 (58%)
PpV	NP_001259272.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	171/284 (60%)
pph-4.1	NP_499603.1	PTZ00239	31..333	CDD:173488	176/301 (58%)
pph-4.1	NP_499603.1	MPP_PP2A_PP4_PP6	31..316	CDD:277360	171/284 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D349967at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830