DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpV and Ppp6c

DIOPT Version :9

Sequence 1:	NP_001259272.1	Gene:	PpV / 31582	FlyBaseID:	FBgn0003139	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_598273.2	Gene:	Ppp6c / 171121	RGDID:	708460	Length:	305	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	227/301 - (75%)
Similarity:	268/301 - (89%)	Gaps:	0/301 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DVDKWIEDVKKCKYLPENELKKLCEMVCDILLEETNILPVSTPVTVCGDIHGQFYDLEQLFRTGG 67
            |:||::|..::|||||||:||:||:.|||:||||:|:.|||||||||||||||||||.:||||||
  Rat     5 DLDKYVEIARQCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGG 69

  Fly    68 QVPHTNYIFMGDFVDRGYYSLETFTRLLTLKARYPSRITLLRGNHETRQITKVYGFFDECFSKYG 132
            |||.|||||||||||||||||||||.||.|||::|.||||||||||:||||:||||:|||.:|||
  Rat    70 QVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYG 134

  Fly   133 NANGWKYCCKVFDLLTIAAIIDEEVLCVHGGLSPEIITLDQIRTIDRNGEIPYKGAFCDLVWSDP 197
            |||.|:||.||||:||:||:|||::|||||||||:|.||||||||:||.|||:||||||||||||
  Rat   135 NANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDP 199

  Fly   198 EDMEYWGQSPRGAGWLFGHNVTKDFMAINNLNLICRAHQLVNEGIKYMFDGKLVTVWSAPNYCYR 262
            ||::.|..||||||||||..||.:|:.||||.|||||||||:||.|:|||.||||||||||||||
  Rat   200 EDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYR 264

  Fly   263 CGNVAAILSFETAEKRQTKIFLAVPDAERVIPKQNTTPYFL 303
            |||:|:|:.|:....|:.|:|.||||:|||||.:.||||||
  Rat   265 CGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpV	NP_001259272.1	PTZ00239	3..303	CDD:173488	225/299 (75%)
PpV	NP_001259272.1	MPP_PP2A_PP4_PP6	3..287	CDD:277360	213/283 (75%)
Ppp6c	NP_598273.2	MPP_PP2A_PP4_PP6	5..289	CDD:277360	213/283 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353392
Domainoid	1	1.000	339	1.000	Domainoid score	I1069
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68273
Inparanoid	1	1.050	502	1.000	Inparanoid score	I1304
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D349967at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	1	1.000	-	-		oto97311
orthoMCL	1	0.900	-	-		OOG6_103044
Panther	1	1.100	-	-	LDO	PTHR45619
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2805
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770