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Protein Alignment Marf and Mfn1

DIOPT Version :9

Sequence 1:	NP_572320.2	Gene:	Marf / 31581	FlyBaseID:	FBgn0029870	Length:	814	Species:	Drosophila melanogaster
Sequence 2:	NP_620432.1	Gene:	Mfn1 / 192647	RGDID:	621460	Length:	741	Species:	Rattus norvegicus

Alignment Length:	752	Identity:	357/752 - (47%)
Similarity:	489/752 - (65%)	Gaps:	30/752 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SPLQIFVRAKKKINDIYGEIEEYVHETTTFINALHAEAEIVDK--AERELFE--SYVYKVAAIRE 131
            |||:.||.|||.|..|:|::.|:|.|.:.|:.|.:...|: |:  .|.:|.|  .|..|:|.|.|
  Rat     6 SPLKHFVLAKKAITAIFGQLLEFVTEGSHFVEATYRNPEL-DRIATEDDLVEIQGYRNKLAVIGE 69

  Fly   132 VLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKL 196
            ||.|.|||||||||||:||||||||||.:|:||||||||||||..|||::|.:||||||||:||.
  Rat    70 VLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKK 134

  Fly   197 NVVNIKQLANALCQEK-LCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNA 260
            :|..:.|||:||..:| |....||.:|||:.:|:|||||:|.|||||.||:..||.|||..||:|
  Rat   135 SVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDA 199

  Fly   261 DVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERC 325
            ||||||.|:|||:...||.|||.|:::|||||||||||||||||:|||..|.    |:.||.|||
  Rat   200 DVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMED----VRRQHMERC 260

  Fly   326 IDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFE 390
            :.||.:||||.:..||..|:|||||:|.|.:|:.:|:|.|...||:|||||.|..|||:||:.||
  Rat   261 LHFLVEELKVVSPLEARNRIFFVSAKEVLNSRMNKAQGMPEGGGALAEGFQARLQEFQNFEQTFE 325

  Fly   391 ECISQSAVKTKFQQHSSRGKSVSGDMKSMLDNIYERITIFRNLKQDQKNLLTERIQGTETQMMQV 455
            ||||||||||||:||:.|.|.:...:|::||::.......|....:::....:|:.....||..:
  Rat   326 ECISQSAVKTKFEQHTIRAKQILDTVKNILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLL 390

  Fly   456 TREMKMKIHNMVEEVEEKVSKALNEEIWRLGVLIDEFNMPFHPERLVLNIYKKELNAHVESGLGS 520
            |.::|.||..:.|||..|||.|:.:||.||.||:|||...|||...||.:||.|||.|:|.|:|.
  Rat   391 TMDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPTPSVLKVYKSELNKHIEDGMGR 455

  Fly   521 NLRARLSMALAMNVESAQTEMTDRMHALVPNEQLLATSTKMVVRTQPFEMLYSLNCQNLCADFQE 585
            ||..|.:..:..::..:|.|:.:.:..|:|..  :......::..:.|::.|.|||..||:||||
  Rat   456 NLADRCTSEVNASILQSQQEIIENLKPLLPAG--IQNKLHTLIPCKKFDLSYDLNCHKLCSDFQE 518

  Fly   586 DLEFKFSWGIAAMIQRFTGKVRERSKKGQPALVNRQSSI----GHSVSTPTTTPVEATPVCLLPA 646
            |:.|:||.|.::::.||.|     |...|..|:.....|    ....||||.....|.|
  Rat   519 DIVFRFSLGWSSLVHRFLG-----STNAQRVLLGLSEPIFQVPRSLASTPTAPSNPAAP------ 572

  Fly   647 PVVAGITPEQLSLISRFAVSSIGSQGTVGGLVVAGVMLKTIGWRVLVGVGALYGCIYLYERLSWT 711
               .....|:|.:.....::|:.|:.::|.:||.||:.||:||:::....::||.:||||||:||
  Rat   573 ---DNAAQEELMITLITGLASLTSRTSMGIIVVGGVIWKTVGWKLISVTLSMYGALYLYERLTWT 634

  Fly   712 NSAKERTFKSQYVRHATKKLKMIVDLTSANCSHQVQQELSSTFARLCRTVDTATTDMNDELKTLD 776
            ..||||.||.|:|.:||:||:|||..||||||||||||:::||||||:.||.....:.:|:..|.
  Rat   635 TRAKERAFKQQFVNYATEKLQMIVKFTSANCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLS 699

  Fly   777 SQLNILEANQKQLKLLRNKANYIQNELDIFEHNYISP 813
            .:::.||..|...|||||||..::.||:.|...::.|
  Rat   700 KEIDQLEKIQNNSKLLRNKAVQLERELENFSKQFLHP 736

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.