DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3847 and hbl-1

DIOPT Version :9

Sequence 1:	NP_572317.2	Gene:	CG3847 / 31577	FlyBaseID:	FBgn0029867	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_001041243.1	Gene:	hbl-1 / 180848	WormBaseID:	WBGene00001824	Length:	982	Species:	Caenorhabditis elegans

Alignment Length:	361	Identity:	64/361 - (17%)
Similarity:	116/361 - (32%)	Gaps:	106/361 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVKYSMVKEEIVPVLIEQDTEVDPEEEPEEDEEHVQ-EDDGQETQ-----YTYAYTTGDD-DDTE 62
            |:|..|.:...|...:....|.:|.:|.....:::. ..||..|.     :..:.|.... |.|.
Worm   375 RLKKHMRESHTVEEQLRAGFESEPAKESASSPKNLSLSKDGSATSPINEIFNLSTTMASILDSTN 439

  Fly    63 TAVVTLSDRDHEALVNAEEVIIDENGHAVTLQELVENS----------TVEEETI---EQGDGTH 114
            .||.:.|..:..:.::|  :.:|.:.....|..|..:|          .:.|...   |.|....
Worm   440 NAVSSTSTTEQPSALSA--LTLDMSSTPSLLSTLAHSSFGVSALDQIKAISENPSFMPEGGINLA 502

  Fly   115 TILHIVPNIHGEEVEEDEELEDGEEVEHDDEFVTVDHEGGELEVEDDEVGSIVFESTIDHAEQDP 179
            :.|.:|.|....:....|:..:||                                    ..:..
Worm   503 SALGVVSNAIKGDTPSPEKQSNGE------------------------------------CRRSS 531

  Fly   180 YGRNKTFYCPNCGNCYSAAGSLKLHMRACLRQRNEISTDERKCKVCSKVFNSVAYLKEHMMRHTG 244
            .|:.|.|.|..||:...:......|.|..:....:::     |:.|:.|.....:|:.|...|.|
Worm   532 SGKIKIFKCKQCGHQSLSKDDQWAHARTHIPAEKQLN-----CQHCNFVTEYKHHLEYHYRNHIG 591

  Fly   245 EQPFRCTRCYRKFVEESKFTAHMESHKHQDKLEAEAVALAAQHGGKKVVVKEFQCAFCSQNFTVV 309
            .:||:|.:|....|.:|...:||:||.:.                     .:|:|..|:
Worm   592 SKPFQCKKCAYNCVNKSMLNSHMKSHTNH---------------------YQFRCMDCT------ 629

  Fly   310 FDVGQVKRRYACDACRDKYSNAEALRQHKQQVEEKR 345
                     ||...|       .:|:.|.::...:|
Worm   630 ---------YATKYC-------HSLKLHLKKYNHRR 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3847	NP_572317.2	C2H2 Zn finger	188..216	CDD:275368	5/27 (19%)
		C2H2 Zn finger	222..242	CDD:275368	5/19 (26%)
		C2H2 Zn finger	250..270	CDD:275368	6/19 (32%)
hbl-1	NP_001041243.1	C2H2 Zn finger	338..358	CDD:275368
		C2H2 Zn finger	363..384	CDD:275368	3/8 (38%)
		C2H2 Zn finger	569..589	CDD:275368	5/19 (26%)
		zf-H2C2_2	581..602	CDD:290200	8/20 (40%)
		C2H2 Zn finger	597..617	CDD:275368	6/19 (32%)
		zf-H2C2_2	609..634	CDD:290200	9/60 (15%)
		C2H2 Zn finger	625..643	CDD:275368	7/39 (18%)
		C2H2 Zn finger	931..951	CDD:275368
		C2H2 Zn finger	959..982	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000