DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3842 and ENV9

DIOPT Version :9

Sequence 1:	NP_001259270.1	Gene:	CG3842 / 31576	FlyBaseID:	FBgn0029866	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_014889.3	Gene:	ENV9 / 854420	SGDID:	S000005772	Length:	330	Species:	Saccharomyces cerevisiae

Alignment Length:	323	Identity:	90/323 - (27%)
Similarity:	142/323 - (43%)	Gaps:	54/323 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 PAYRKANRIDGKVVIVTGCNTGIGKETVLELAKRGARVYMACRDPGRCEAARLDIMDRSRNQ--- 125
            |.|..|  ::.|:.:|||.|||||..|||.|...|..||:..|:..:...|..:|:..::.:
Yeast     8 PYYDPA--VERKIAVVTGGNTGIGWYTVLHLYLHGFVVYICGRNSHKISKAIQEILAEAKKRCHE 70

  Fly   126 -------------------QLFNRTLDLGSLQSVRNFVERFKAEESRLDILINNAGVMACPRTLT 171
                               .|....|||..|:.|.....:....|..:|:|:||||:||.|..:|
Yeast    71 DDDGSSPGAGPGPSIQRLGSLHYIHLDLTDLKCVERAALKILKLEDHIDVLVNNAGIMAVPLEMT 135

  Fly   172 ADGFEQQFGVNHLGHFLLTNLLLDRLKHSSPSRIVVVSSAAH----LFGRINRE-DLMSEKNYSK 231
            .||||.|...|::.||:.|..||..|:|.. .||:.:||..|    ::.::::. |......::.
Yeast   136 KDGFEVQLQTNYISHFIFTMRLLPLLRHCR-GRIISLSSIGHHLEFMYWKLSKTWDYKPNMLFTW 199

  Fly   232 FFGAYSQSKLANILFTLKLSTILKDTGVTVNCCHPG-VVRTEINRHFSGPGWMKTAL-------- 287
            |  .|:.||.|.|..|..|:  :|...|.....||| |:.|.:..:     |.:..:
Yeast   200 F--RYAMSKTALIQCTKMLA--IKYPDVLCLSVHPGLVMNTNLFSY-----WTRLPIVGIFFWLL 255

  Fly   288 -QKGSLYFFKTPKAGAQTQLRLALDPQL--EGSTGGYYSDCMRWPLFPWVRN---MQTADWLW 344
             |....:|..:.:.|:...|:.||||.|  |...|.|::...:.....:|.|   ...:.|:|
Yeast   256 FQVVGFFFGVSNEQGSLASLKCALDPNLSVEKDNGKYFTTGGKESKSSYVSNNVDEAASTWIW 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_001259270.1	FabG	71..319	CDD:223959	81/286 (28%)
CG3842	NP_001259270.1	NADB_Rossmann	74..347	CDD:304358	87/313 (28%)
ENV9	NP_014889.3	NADB_Rossmann	17..318	CDD:419666	86/310 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I2553
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I1353
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		otm46796
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1905
SonicParanoid	1	1.000	-	-		X72
TreeFam	0	0.000	Not matched by this tool.
	10	9.790