Protein Alignment CG3842 and RDH14

DIOPT Version :10

• Sequence 1: NP_572316.1
• Gene: CG3842 / 31576
• FlyBaseID: FBgn0029866
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_065956.1
• Gene: RDH14 / 57665
• HGNCID: 19979
• Length: 336
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 152/319 - (47%)
• Similarity: 191/319 - (59%)
• Gaps: 20/319 - (6%)

  Fly    54 MWLLRKCIQGPAYRKANR------IDGKVVIVTGCNTGIGKETVLELAKRGARVYMACRDPGRCE 112
            :||..:...||..::..|      :.||.|::||.|:|:|:.|..||.:.||||.|.|||..|.|
Human    17 LWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAE 81

  Fly   113 AARLDIMDRSRNQ-------------QLFNRTLDLGSLQSVRNFVERFKAEESRLDILINNAGVM 164
            .|...:....|..             :|..|.|||.||:|||.|.:....||.|||:||||||:.
Human    82 EAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIF 146

  Fly   165 ACPRTLTADGFEQQFGVNHLGHFLLTNLLLDRLKHSSPSRIVVVSSAAHLFGRINREDLMSEKNY 229
            .||...|.||||.|||||||||||||||||..||.|:|||||||||..:.:|.||.:||.||::|
Human   147 QCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSY 211

  Fly   230 SKFFGAYSQSKLANILFTLKLSTILKDTGVTVNCCHPGVVRTEINRHFSGPGWMKTALQKGSLYF 294
            :|.| .||:|||||||||.:|:..|:.|.||||..|||:|||.:.||...|..:|......|..|
Human   212 NKSF-CYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAF 275

  Fly   295 FKTPKAGAQTQLRLALDPQLEGSTGGYYSDCMRWPLFPWVRNMQTADWLWRESEKLLGL 353
            ||||..||||.:.||..|::||.:|.|:.||....|.|...:...|..||..||.::||
Human   276 FKTPVEGAQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGL 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_572316.1	Rossmann-fold NAD(P)(+)-binding proteins	74..347	CDD:473865	143/285 (50%)
RDH14	NP_065956.1	retinol-DH_like_SDR_c	43..328	CDD:212495	143/285 (50%)