DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3842 and rdh12l

DIOPT Version :9

Sequence 1:	NP_001259270.1	Gene:	CG3842 / 31576	FlyBaseID:	FBgn0029866	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001009912.1	Gene:	rdh12l / 494176	ZFINID:	ZDB-GENE-040801-48	Length:	291	Species:	Danio rerio

Alignment Length:	289	Identity:	148/289 - (51%)
Similarity:	192/289 - (66%)	Gaps:	4/289 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 AYRKANRIDGKVVIVTGCNTGIGKETVLELAKRGARVYMACRDPGRCEAARLDIMDRSRNQQLFN 129
            ::..|.|:|||.|::||.||||||||.::|||||||:.|||||..:.|||..::.|.|.||.:|.
Zfish     4 SWSSAARLDGKTVLITGANTGIGKETAIDLAKRGARIIMACRDMEKAEAALKEVKDSSGNQDVFI 68

  Fly   130 RTLDLGSLQSVRNFVERFKAEESRLDILINNAGVMACPRTLTADGFEQQFGVNHLGHFLLTNLLL 194
            .:|||...:|:|.|.|:...||.:::|||||||||.||...||||||.|.||||:||||||.|||
Zfish    69 SSLDLSDSKSIRGFAEKINKEEKQVNILINNAGVMVCPYGKTADGFEMQIGVNHMGHFLLTYLLL 133

  Fly   195 DRLKHSSPSRIVVVSSAAHLFGRINREDLMSEKNYSKFFGAYSQSKLANILFTLKLSTILKDTGV 259
            |.:|.|:|:||:.|||.||.:|.||.||:.|||||.| ..||.||||||:|||..|:..|:.|||
Zfish   134 DLIKRSAPARIINVSSTAHQWGTINLEDINSEKNYDK-QKAYCQSKLANVLFTRSLAKRLEGTGV 197

  Fly   260 TVNCCHPGVVRTEINRHFSGPGWMKTALQKGSLYFFKTPKAGAQTQLRLALDPQLEGSTGGYYSD 324
            |....|||||:|::.||.|.|   :.|:...:..|.||...||||.:..|:||.|:..:|.||||
Zfish   198 TAYSLHPGVVQTDLWRHLSKP---QQAVMWFTKPFTKTSVQGAQTSIYCAVDPALQTESGKYYSD 259

  Fly   325 CMRWPLFPWVRNMQTADWLWRESEKLLGL 353
            |..........:.:.|..||..|.::|.:
Zfish   260 CAPAKAAKAAMDDEVAQRLWELSCRMLNI 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_001259270.1	FabG	71..319	CDD:223959	136/247 (55%)
CG3842	NP_001259270.1	NADB_Rossmann	74..347	CDD:304358	143/272 (53%)
rdh12l	NP_001009912.1	PRK06197	5..291	CDD:235737	148/288 (51%)
rdh12l	NP_001009912.1	NADB_Rossmann	13..282	CDD:304358	143/272 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	1	1.000	-	-		mtm6476
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.690