DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3842 and Rdh13

DIOPT Version :9

Sequence 1:	NP_001259270.1	Gene:	CG3842 / 31576	FlyBaseID:	FBgn0029866	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001101938.1	Gene:	Rdh13 / 361504	RGDID:	1304959	Length:	334	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	150/308 - (48%)
Similarity:	187/308 - (60%)	Gaps:	18/308 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LLRKCIQGPAYRKANRIDGKVVIVTGCNTGIGKETVLELAKRGARVYMACRDPGRCEAARLDIMD 120
            ||:..:.|.|......|.|:.|||||.||||||:|.|||||||..:.:||||..:||||..||..
  Rat    20 LLKDYVAGGACPSKATIPGRTVIVTGANTGIGKQTALELAKRGGNIILACRDREKCEAAAKDIRG 84

  Fly   121 RSRNQQLFNRTLDLGSLQSVRNFVERFKAEESRLDILINNAGVMACPRTLTADGFEQQFGVNHLG 185
            .:.|.::....|||.||:|:|.|..:...||.|:|||:|||.||.||...|.||||.||||||||
  Rat    85 ETLNPRVRAEHLDLASLKSIREFAGKIIKEEERVDILVNNAAVMRCPHWTTEDGFEMQFGVNHLG 149

  Fly   186 HFLLTNLLLDRLKHSSPSRIVVVSSAAHLFGRINREDLMSE-KNYSKFFGAYSQSKLANILFTLK 249
            ||||||||||:||.|:||||:.:||.||:.|.|:.|||..: |.|.. ..||.|||||.:|||.:
  Rat   150 HFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFEDLNWQIKKYDT-KAAYCQSKLAVVLFTKE 213

  Fly   250 LSTILKDTGVTVNCCHPGVVRTEINRH-------FSGPGWMKTALQKGSLYF--FKTPKAGAQTQ 305
            ||..|:.||||||..||||.|||:.||       |||       ...|..::  ||:|:..||..
  Rat   214 LSRRLQGTGVTVNALHPGVARTELGRHTGMHNSAFSG-------FMLGPFFWLLFKSPQLAAQPS 271

  Fly   306 LRLALDPQLEGSTGGYYSDCMRWPLFPWVRNMQTADWLWRESEKLLGL 353
            ..||:..:||..:|.|:.........|...:.:.|..||.||..|:||
  Rat   272 TYLAVAEELESVSGKYFDGLREKAPSPEAEDEEVARRLWTESAHLVGL 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_001259270.1	FabG	71..319	CDD:223959	135/257 (53%)
CG3842	NP_001259270.1	NADB_Rossmann	74..347	CDD:304358	140/282 (50%)
Rdh13	NP_001101938.1	NADB_Rossmann	38..313	CDD:419666	140/282 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I2082
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53570
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.730