Protein Alignment CG3842 and Hsd17b1

DIOPT Version :10

• Sequence 1: NP_572316.1
• Gene: CG3842 / 31576
• FlyBaseID: FBgn0029866
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_034605.1
• Gene: Hsd17b1 / 15485
• MGIID: 105077
• Length: 344
• Species: Mus musculus
• Alignment Length: 356
• Identity: 82/356 - (23%)
• Similarity: 119/356 - (33%)
• Gaps: 109/356 - (30%)

  Fly    72 IDGKVVIVTGCNTGIGKETVLELA---KRGARVYMACRD-----------------PGRCEAARL 116
            :|..||::|||::|||....:.||   .:..:||...||                 ||..|...|
Mouse     1 MDPTVVLITGCSSGIGMHLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARTQGCPPGSLEILEL 65

  Fly   117 DIMDRSRNQQLFNRTLDLGSLQSVRNFVERFKAEESRLDILINNAGVMACPRTLTADGFEQQFG- 180
            |:.|          :..:.:.|:.        ..|.|:|:|:.|||     |.|        ||
Mouse    66 DVRD----------SKSVAAAQAC--------VTEGRVDVLVCNAG-----RGL--------FGP 99

  Fly   181 --------------VNHLGHFLLTNLLLDRLKHSSPSRIVVVSSAAHLFGRINREDLMSEKNYSK 231
                          ||.||...:....|..:|.....|::|.:|...|.|             ..
Mouse   100 LEAHELNAVGAVLDVNVLGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMG-------------LP 151

  Fly   232 FFGAYSQSKLANILFTLKLSTILKDTGVTVNCCHPGVVRTEI-NRHFSGPGWMKTALQKGSLYFF 295
            |...|..||.|.......|:.:|...||.|:....|.|.|.. .:...|||.........:.:.|
Mouse   152 FHEVYCASKFALEGLCESLAILLPLFGVHVSLIECGAVHTAFYEKLVGGPGGALERADAQTRHLF 216

  Fly   296 KTPKAGAQTQLRLALDPQLEGSTGGYYSDCMRWPLFPWVRNMQTADWLWRESEKLLGLPPLEPPP 360
            .....|.:..|..|.||:   .....:...||.|. |.:|...|        .:.|.|..:.
Mouse   217 AHYLRGYEQALSEAQDPE---EVTELFLTAMRAPQ-PALRYFST--------NRFLPLARMR--- 266

  Fly   361 PVQSPTQNGNGTQNGNGSSSASA---SASSN 388
                       |::.:|||..:|   .|.||
Mouse   267 -----------TEDPSGSSYVAAMHQEAFSN 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_572316.1	Rossmann-fold NAD(P)(+)-binding proteins	74..347	CDD:473865	71/308 (23%)
Hsd17b1	NP_034605.1	Rossmann-fold NAD(P)(+)-binding proteins	4..260	CDD:473865	71/311 (23%)