Protein Alignment CG3842 and DHRS9

DIOPT Version :10

• Sequence 1: NP_572316.1
• Gene: CG3842 / 31576
• FlyBaseID: FBgn0029866
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001276692.1
• Gene: DHRS9 / 10170
• HGNCID: 16888
• Length: 379
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 86/360 - (23%)
• Similarity: 137/360 - (38%)
• Gaps: 92/360 - (25%)

  Fly    36 FWAWAVLIFLIVLGILL---FMWLLRKCIQGPAYRKANRIDGKVVIVTGCNTGIGKETVLELAKR 97
            ||         |||:|:   |:|..:..:      |...|..|.:.:|||::|.|........|:
Human    63 FW---------VLGLLILCGFLWTRKGKL------KIEDITDKYIFITGCDSGFGNLAARTFDKK 112

  Fly    98 GARVYMACRDPGRCEAARLDIMDRSRNQQLFNRTLDLGSLQSVRNFVERFKAE--ESRLDILINN 160
            |..|..||.......|.:.:..:|.|..     .||:...::|:...:..|.:  |..|..||||
Human   113 GFHVIAACLTESGSTALKAETSERLRTV-----LLDVTDPENVKRTAQWVKNQVGEKGLWGLINN 172

  Fly   161 A---GVMACPRTLTADGFEQQFGVNHLGHFLLTNLLLDRLKHSSPSRIVVVSSAAHLFGRINRED 222
            |   ||:|....||.:.:.:...||..|...:|..:|..:| .:..|::.|||..   ||:
Human   173 AGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVK-KAQGRVINVSSVG---GRL---- 229

  Fly   223 LMSEKNYSKFFGAYSQSKLANILFTLKLSTILKDTGVTVNCCHPGVVRT---------------- 271
                   :...|.|:.||.|...|...|...:|..||.|:|..||:.:|
Human   230 -------AIVGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNLADPVKVIEKKLAIW 287

  Fly   272 -----EINRHFSGPGWMKTALQKGSLYFFKTPKAGAQTQLRLALDPQLEGSTGGYYSDCM---RW 328
                 :|.:.: |.|:::.:|.|         ..|.::.:.:.|.|.:|         ||   ..
Human   288 EQLSPDIKQQY-GEGYIEKSLDK---------LKGNKSYVNMDLSPVVE---------CMDHALT 333

  Fly   329 PLFPWVRNMQTADWLWRESEKLLGLPPLEPPPPVQ 363
            .|||........|      .|:..:|....|..:|
Human   334 SLFPKTHYAAGKD------AKIFWIPLSHMPAALQ 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_572316.1	Rossmann-fold NAD(P)(+)-binding proteins	74..347	CDD:473865	72/301 (24%)
DHRS9	NP_001276692.1	type2_17beta_HSD-like_SDR_c	90..366	CDD:187665	76/318 (24%)