DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3842 and rdh11

DIOPT Version :9

Sequence 1:	NP_001259270.1	Gene:	CG3842 / 31576	FlyBaseID:	FBgn0029866	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_031751072.1	Gene:	rdh11 / 100485470	XenbaseID:	XB-GENE-5943090	Length:	327	Species:	Xenopus tropicalis

Alignment Length:	335	Identity:	127/335 - (37%)
Similarity:	180/335 - (53%)	Gaps:	22/335 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LCFRGFWAWAVLIFLIVLGILLFMWLLRKCIQGPAYRKANRIDGKVVIVTGCNTGIGKETVLELA 95
            ||..|   |    |...:|:::.:.|.|:....|: :.:..:.||..||||.||||||...::||
Frog     7 LCHPG---W----FCCCVGLIIILRLRRRKPWDPS-KCSVSLAGKTAIVTGANTGIGKCVAMDLA 63

  Fly    96 KRGARVYMACRDPGRCEAARLDIMDRSRNQQLFNRTLDLGSLQSVRNFVERFKAEESRLDILINN 160
            :|.|||.:|||...|.:.|..:|..::.|..:....||..|:.|||.|.:|...:|.||||||||
Frog    64 RRNARVILACRSRERGQRALEEIRRQTGNGAVLLEMLDTSSMASVRAFADRILQQEKRLDILINN 128

  Fly   161 AGVMACPRTLTADGFEQQFGVNHLGHFLLTNLLLDRLKHSSPSRIVVVSSAAHLFGRINREDLMS 225
            ||....|.::||:|.|..|..||||.|||||||...::.|:|||||.|||..|..|.|:...|..
Frog   129 AGASGLPHSMTAEGLENTFATNHLGPFLLTNLLTGLMRKSAPSRIVFVSSFNHKNGEIHLSCLRG 193

  Fly   226 EK------NYSKFFGAYSQSKLANILFTLKLSTILKDTGVTVNCCHPGVVRTEINRHFSGPGWMK 284
            :.      :|     .|:.|||.||:...:.:..|:.|||||....||:|.||..|::|  .:::
Frog   194 QNIRGFRPDY-----PYNCSKLMNIMCANEFARRLRGTGVTVTSLDPGIVMTEAVRYYS--IFIR 251

  Fly   285 TALQKGSLYFFKTPKAGAQTQLRLALDPQLEGSTGGYYS-DCMRWPLFPWVRNMQTADWLWRESE 348
            ...:....:||:||:.||.:.:..|:..:.||.|..|.. |||.....|..|:......||...|
Frog   252 LIFKSIGFFFFRTPEEGAVSTIFCAVSEEAEGLTEKYIDCDCMLALPSPAARDPPVTAKLWEACE 316

  Fly   349 KLLGLPPLEP 358
            :.:||||..|
Frog   317 QAVGLPPSPP 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_001259270.1	FabG	71..319	CDD:223959	103/253 (41%)
CG3842	NP_001259270.1	NADB_Rossmann	74..347	CDD:304358	112/279 (40%)
rdh11	XP_031751072.1	NADB_Rossmann	42..313	CDD:419666	111/277 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D414554at33208
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010