DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3823 and TTPAL

DIOPT Version :9

Sequence 1:	NP_572313.1	Gene:	CG3823 / 31573	FlyBaseID:	FBgn0029863	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001034288.1	Gene:	TTPAL / 79183	HGNCID:	16114	Length:	342	Species:	Homo sapiens

Alignment Length:	264	Identity:	65/264 - (24%)
Similarity:	119/264 - (45%)	Gaps:	23/264 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LNEKAEDQLMTTRISDLQDWLQAQ-PQLPQNISRLLLRRFLHTTRGDLSAAQRLLELNYGLRNKH 67
            |.||.|.:|..  :..|:|.::.: |.|..::....|.|||...:.|...|.:||...:..|...
Human    47 LQEKPEWRLRD--VQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRSW 109

  Fly    68 AHIFIDRDPLDASSQQLLQVADLVPLPGLTPENNKLLFYRLIDFDADKFNFTAAIKVFFMVADCR 132
            ..:|.:..|  ::.:.:|....|..||...|....::..|...:....:..|..|:..::..:
Human   110 PEVFNNLKP--SALKDVLASGFLTVLPHTDPRGCHVVCIRPDRWIPSNYPITENIRAIYLTLE-- 170

  Fly   133 FATENEERLSDGEIPVFDMAGYTLR-------HLTKTALGALRVYMKFVQEAHPVRLKEIHVLNC 190
            ...::||...:|.:.:.|..|.:|.       .:.|..:|.|       |:..|:|:|.:||:|.
Human   171 KLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGIL-------QDGFPIRIKAVHVVNE 228

  Fly   191 PSYVDKVMAVVKPFIKGEVFKLIHFHLPNADTPYRHFPRSMLPEEYGGEAGKMSDLKLQWMQLLK 255
            |.....:.|::|||:|.::......|..:.::.:.:.|||:||:||||.||::.  ...|..:|.
Human   229 PRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRSILPKEYGGTAGELD--TATWNAVLL 291

  Fly   256 EQRD 259
            ...|
Human   292 ASED 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3823	NP_572313.1	SEC14	90..239	CDD:238099	38/155 (25%)
TTPAL	NP_001034288.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		CRAL_TRIO_N	56..102	CDD:215024	12/47 (26%)
		SEC14	121..277	CDD:238099	39/164 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920