DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3823 and Clvs1

DIOPT Version :9

Sequence 1:	NP_572313.1	Gene:	CG3823 / 31573	FlyBaseID:	FBgn0029863	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001342112.1	Gene:	Clvs1 / 74438	MGIID:	1921688	Length:	354	Species:	Mus musculus

Alignment Length:	281	Identity:	59/281 - (20%)
Similarity:	120/281 - (42%)	Gaps:	32/281 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VHLNEKAEDQLMTTRISDLQDWLQAQPQLP-QNISRLLLRRFLHTTRGDLSAAQRLLELNYGLRN 65
            :.|||..:  ::...|..::|.:..:|.:. .......:.|||...:...:.|.|||...:..|.
Mouse    40 LELNENPD--ILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQ 102

  Fly    66 KHAHIFIDRDPLDASSQQLLQVADLVPLPGLTPEN-----NKLLFYRLIDFDADKFNFTAAIKVF 125
            .:..:|.:....|...::.|    :...||:. ||     .|:|.....::|..:.:||..::..
Mouse   103 LNLDMFKNFKADDPGIKRAL----IDGFPGVL-ENRDHYGRKILLLFAANWDQSRNSFTDILRAI 162

  Fly   126 FMVADCRFATENEERLSDGEIPVFDMAGYTLRHLTKTALGALRVYMKFVQEAHPVRLKEIHVLNC 190
            .:  ......|:.|...:|.|.:.|.:.::.:..:|.....|::.::.:|::.|.|...:|.:|.
Mouse   163 LL--SLEVLIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQ 225

  Fly   191 PSYVDKVMAVVKPFIKGEVFKLIHFHLPNADTPYRHFPRSMLPEEYGG-----EAGKMSDLKLQW 250
            |.|:..:..::|||:|.:..|.|..|..|.::.::......||.|:||     :.|       .|
Mouse   226 PWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMG-------TW 283

  Fly   251 MQLL-----KEQRDYLMDTEN 266
            .:.|     .::.||...:.|
Mouse   284 ARTLLGPDYSDENDYTHTSYN 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3823	NP_572313.1	SEC14	90..239	CDD:238099	36/158 (23%)
Clvs1	NP_001342112.1	CRAL_TRIO_N	51..97	CDD:215024	10/45 (22%)
		CRAL_TRIO	125..274	CDD:366224	35/151 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835962
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750