DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3823 and sec14l8

DIOPT Version :9

Sequence 1:	NP_572313.1	Gene:	CG3823 / 31573	FlyBaseID:	FBgn0029863	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001093463.1	Gene:	sec14l8 / 558964	ZFINID:	ZDB-GENE-060526-180	Length:	395	Species:	Danio rerio

Alignment Length:	261	Identity:	58/261 - (22%)
Similarity:	102/261 - (39%)	Gaps:	41/261 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MTTRISDL---------------QDWLQAQPQLPQNISRLLLRRFLHTTRGDLSAAQRLLELNYG 62
            |:.|:.||               ||.|   ||.|......|| |:|.....:|..::.:|..:..
Zfish     1 MSGRVGDLSVKQAEALAQFREKVQDVL---PQCPSQSDHFLL-RWLRARNFNLQKSEAMLRKHIE 61

  Fly    63 LRNKHAHIFIDRDPLDASSQQLLQVADLVPLPGLTPENNK--LLFYRLIDFDADKFNFTAAIK-- 123
            .| ||..:    |.: .:..|:.:|.|.....|:...:.:  .::|.:|.....|....:|.|
Zfish    62 FR-KHMKV----DTI-TTEWQVPEVIDKYLSGGMCGHDREGSPVWYDVIGPLDPKGLMHSASKQD 120

  Fly   124 -VFFMVADCRFATENEERLS-------DGEIPVFDMAGYTLRHLTKTALGALRVYMKFVQEAHPV 180
             :...|.||....::.:|.|       :....|:|..|..::||.|.|:......:...::.:|.
Zfish   121 LIKSKVRDCEILQKDCDRQSERLGRNIESITMVYDCEGLGMKHLYKPAIETYGEVLTMFEDNYPE 185

  Fly   181 RLKEIHVLNCPSYVDKVMAVVKPFIKGEV-FKLIHFHLPNADTPYRHFPRSMLPEEYGGEAGKMS 244
            .||.:.|:..|........:||.|:..:. .|:|.......:...::.....||..||   ||::
Zfish   186 GLKRLFVIKAPKLFPVAYNLVKHFLSEDTRRKVIVLGSNWQEVLQKYIDPEELPAYYG---GKLT 247

  Fly   245 D 245
            |
Zfish   248 D 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3823	NP_572313.1	SEC14	90..239	CDD:238099	32/161 (20%)
sec14l8	NP_001093463.1	CRAL_TRIO_N	13..59	CDD:215024	12/49 (24%)
		SEC14	78..246	CDD:214706	35/170 (21%)
		GOLD_2	304..382	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810