Protein Alignment CG3823 and SEC14L4

DIOPT Version :10

• Sequence 1: NP_572313.1
• Gene: CG3823 / 31573
• FlyBaseID: FBgn0029863
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_777637.1
• Gene: SEC14L4 / 284904
• HGNCID: 20627
• Length: 406
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 72/331 - (21%)
• Similarity: 116/331 - (35%)
• Gaps: 78/331 - (23%)

  Fly    13 MTTRISD---------------LQDWLQAQPQLPQNISRLLLRRFLHTTRGDLSAAQRLLELNYG 62
            |::|:.|               |||.|   |.|| |.....|.|:|.....||..::.:|..:..
Human     1 MSSRVGDLSPQQQEALARFRENLQDLL---PILP-NADDYFLLRWLRARNFDLQKSEDMLRRHME 61

  Fly    63 LRNKHAHIFIDRDPLDA-SSQQLLQVADLVPLPGLTPENNKLLFYRLIDFDADKFNFTAA----- 121
            .|.:.     |.|.:.. ...:::|:.|...|.|...|...:.|..:...|......:|:
Human    62 FRKQQ-----DLDNIVTWQPPEVIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDMI 121

  Fly   122 ---IKVF-FMVADCRFATENEERLSDGEIPVFDMAGYTLRHLTKTALGALRVYMKFVQEAHPVRL 182
               |||. .::.:|...|:...|..:..:.||||.|.:|:||.|.|:...:.:...::..:|..|
Human   122 RKRIKVCELLLHECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEANYPETL 186

  Fly   183 KEIHVLNCPSYVDKVMAVVKPFIKGEVFKLIHFHLPNADTPYRHF-------------------- 227
            |.:.|:..|........:||.|:..|..:.|.....|.......|
Human   187 KNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPDQLPVEFGGTMTDPDGN 251

  Fly   228 PRSMLPEEYGGEAGK----MSDLKLQWMQLLKEQRDYLMDTEN----------WQINKIKKNGQR 278
            |:.:....||||..|    ...::||:.......|...:..||          ||.
Human   252 PKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPGCVLRWQF--------- 307

  Fly   279 KSSDSG 284
             :||.|
Human   308 -ASDGG 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3823	NP_572313.1	SEC14	90..239	CDD:469559	37/177 (21%)
SEC14L4	NP_777637.1	CRAL_TRIO_N	13..59	CDD:215024	14/49 (29%)
		SEC14	76..244	CDD:214706	36/167 (22%)
		GPCR_chapero_1	284..381	CDD:480652	8/39 (21%)