Protein Alignment CG3823 and CLVS2

DIOPT Version :10

• Sequence 1: NP_572313.1
• Gene: CG3823 / 31573
• FlyBaseID: FBgn0029863
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 66/307 - (21%)
• Similarity: 129/307 - (42%)
• Gaps: 38/307 - (12%)

  Fly     1 MVHLN--------EKAEDQL------MTTRISDLQDWLQAQPQLP-QNISRLLLRRFLHTTRGDL 50
            |.||.        |||..:|      :...|.:::|.:..:|.:. .......:.|||...:...
Human     1 MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHH 65

  Fly    51 SAAQRLLELNYGLRNKHAHIFIDRDPLDASSQQLLQVADLVP--LPGLTPENNKLLFYRLIDFDA 113
            ..|.|||...:..|.::..:|......|...:|.|:  |..|  |..|.....|:|.....::|.
Human    66 FEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALK--DGFPGGLANLDHYGRKILVLFAANWDQ 128

  Fly   114 DKFNFTAAIKVFFMVADCRFATENEERLSDGEIPVFDMAGYTLRHLTKTALGALRVYMKFVQEAH 178
            .::.....::...:..:...  |:.|...:|.:.:.|.:.:|.:..:|.....||:.::.:|::.
Human   129 SRYTLVDILRAILLSLEAMI--EDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSF 191

  Fly   179 PVRLKEIHVLNCPSYVDKVMAVVKPFIKGEVFKLIHFHLPNADTPYRHFPRSMLPEEYGG----- 238
            |.|...||.:|.|.|:..:..|::||:|.:..|.|..|..|.::.::.....:||.|:||
Human   192 PARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPY 256

  Fly   239 EAGKMSDLKLQWMQLL-----KEQRDYLMDTENWQINKIKKNGQRKS 280
            :.|       .|.:.|     .:..:|.:|:.:..:.:::|....||
Human   257 DMG-------TWARTLLDHEYDDDSEYNVDSYSMPVKEVEKELSPKS 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3823	NP_572313.1	SEC14	90..239	CDD:469559	35/155 (23%)
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	10/45 (22%)
		SEC14	101..251	CDD:469559	34/153 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		3/10 (30%)